Western Blot (WB)
(Western blot analysis of CCDC55 in human brain tissue lysate with CCDC55 antibody at (A) 0.5 and (B) 1 μg/mL)
Chicken CCDC55 Polyclonal Antibody | anti-NSRP1 antibody
CCDC55 Antibody
Gene Names
NSRP1; CCDC55; NSrp70; HSPC095
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunofluorescence
Purity
CCDC55 Antibody is affinity chromatography purified via peptide column.
Synonyms
CCDC55; Polyclonal Antibody; CCDC55 Antibody; NSrp70; HSPC095; NSRP70; Nuclear speckle splicing regulatory protein 1; Coiled-coil domain-containing protein 55; nuclear speckle splicing regulatory protein 1; anti-NSRP1 antibody
Host
Chicken
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgY
Specificity
At least three isoforms are known to exist; this antibody will detect all three.
Purity/Purification
CCDC55 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
558
Applicable Applications for anti-NSRP1 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes
CCDC55 antibody can be used for detection of CCDC55 by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunofluorescence starting at 20 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
CCDC55 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human CCDC55.
Buffer
CCDC55 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
CCDC55 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of CCDC55 in human brain tissue lysate with CCDC55 antibody at (A) 0.5 and (B) 1 μg/mL)
Western Blot (WB)
(Western blot analysis of CCDC55 in human brain tissue lysate with CCDC55 antibody at (A) 0.5 and (B) 1 μg/mL)
Immunofluorescence (IF)
(Immunofluorescence of CCDC55 in mouse brain cells with CCDC55 antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of CCDC55 in mouse brain cells with CCDC55 antibody at 20 μg/mL.)
Related Product Information for anti-NSRP1 antibody
CCDC55 Antibody: CCDC55, also known as Nuclear speckle-related protein 70 (NSrp70), was initially identified by the NIH Mammalian Gene Collection. Nuclear speckles are known to be the storage sites of mRNA splicing regulators. CCDC55 has been suggested to modulate alternative pre-mRNA splicing in vivo. It co-localizes and physically interacts with the SR proteins SC35 and ASF/SF2, essential splicing factors which are required for constitutive splicing and can regulate alternative mRNA splicing. Loss of CCDC55 in mice leads to early embryonic lethality highlights the importance of the functional role of CCDC55.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
66,390 Da
NCBI Official Full Name
nuclear speckle splicing regulatory protein 1 isoform 1
NCBI Official Synonym Full Names
nuclear speckle splicing regulatory protein 1
NCBI Official Symbol
NSRP1
NCBI Official Synonym Symbols
CCDC55; NSrp70; HSPC095
NCBI Protein Information
nuclear speckle splicing regulatory protein 1; coiled-coil domain containing 55; nuclear speckle-related protein 70; coiled-coil domain-containing protein 55
UniProt Protein Name
Nuclear speckle splicing regulatory protein 1
Protein Family
UniProt Gene Name
NSRP1
UniProt Synonym Gene Names
CCDC55; NSRP70; NSrp70
UniProt Entry Name
NSRP1_HUMAN
Uniprot Description
CCDC55: RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Belongs to the NSRP1 family.
Protein type: RNA splicing; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component: nuclear speck; ribonucleoprotein complex; nucleus
Molecular Function: mRNA binding; protein binding
Biological Process: RNA splicing; nucleocytoplasmic transport; developmental process; mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome
Research Articles on NSRP1
Similar Products
Product Notes
The NSRP1 nsrp1 (Catalog #AAA151410) is an Antibody produced from Chicken and is intended for research purposes only. The product is available for immediate purchase. The CCDC55 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CCDC55 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). CCDC55 antibody can be used for detection of CCDC55 by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunofluorescence starting at 20 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the NSRP1 nsrp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCDC55, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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