Rabbit anti-Human CCDC53 Polyclonal Antibody | anti-CCDC53 antibody
CCDC53 Antibody
Gene Names
CCDC53; CGI-116
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G Purified
Synonyms
CCDC53; Polyclonal Antibody; CCDC53 Antibody; WASH complex subunit CCDC53; AD-016; CGI-116; x0009; Coiled-coil domain-containing protein 53; anti-CCDC53 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
194
Applicable Applications for anti-CCDC53 antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human WASH complex subunit CCDC53 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-242371
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-CCDC53 antibody
Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,173 Da
NCBI Official Full Name
WASH complex subunit CCDC53 isoform 1
NCBI Official Synonym Full Names
coiled-coil domain containing 53
NCBI Official Symbol
CCDC53
NCBI Official Synonym Symbols
CGI-116
NCBI Protein Information
WASH complex subunit CCDC53
UniProt Protein Name
WASH complex subunit CCDC53
Protein Family
UniProt Gene Name
CCDC53
UniProt Entry Name
CCD53_HUMAN
Uniprot Description
CCDC53: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Belongs to the CCDC53 family.
Chromosomal Location of Human Ortholog: 12q23.2
Cellular Component: actin cytoskeleton; early endosome; intracellular membrane-bound organelle
Molecular Function: protein binding
Biological Process: protein transport
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Product Notes
The CCDC53 ccdc53 (Catalog #AAA1493112) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCDC53 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCDC53 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the CCDC53 ccdc53 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCDC53, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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