Western Blot (WB)
(CCDC22 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the CCDC22 antibody detected the CCDC22 protein (arrow).)
Rabbit anti-Human CCDC22 Polyclonal Antibody | anti-CCDC22 antibody
CCDC22, CT (CCDC22, CXorf37, Coiled-coil domain-containing protein 22) (PE)
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Western Blot (WB)
(CCDC22 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the CCDC22 antibody detected the CCDC22 protein (arrow).)
Western Blot (WB)
(CCDC22 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the CCDC22 antibody detected the CCDC22 protein (arrow).)
Immunohistochemistry (IHC)
(CCDC22 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCDC22 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(CCDC22 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCDC22 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein containing a coiled-coil domain. The encoded protein functions in the regulation of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) by interacting with COMMD (copper metabolism Murr1 domain-containing) proteins. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. [provided by RefSeq, Aug 2013]
Uniprot Description
CCDC22: May be involved in X-linked syndromic mental retardation (PubMed:21826058). CCDC22 expression has been found to be down-regulated in a family with a phenotype consistent with X- linked syndromic mental retardation, and carrying variant Ala-17. In addition to intellectual disability, affected individuals have cardiac and skeletal abnormalities. Belongs to the CCDC22 family.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: Xp11.23
Cellular Component: endosome
Molecular Function: protein binding
Biological Process: Golgi to plasma membrane transport; protein transport; cellular copper ion homeostasis; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytoplasmic sequestering of NF-kappaB; negative regulation of I-kappaB kinase/NF-kappaB cascade
Research Articles on CCDC22
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Product Notes
The CCDC22 ccdc22 (Catalog #AAA6281672) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCDC22, CT (CCDC22, CXorf37, Coiled-coil domain-containing protein 22) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCDC22 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CCDC22 ccdc22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCDC22, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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