SDS-Page
(Gel: 8%SDS-PAGE lysate: 40 ¦Œg, Lane 1-2: K562 cell and Mouse testis tissue lysates, Primary antibody: 46420£¨CCDC181 Antibody) at dilution 1/250 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds)
Rabbit anti-Human CCDC181 Polyclonal Antibody | anti-CCDC181 antibody
CCDC181 Antibody
Gene Names
CCDC181; C1orf114
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
CCDC181; Polyclonal Antibody; CCDC181 Antibody; C1orf114; anti-CCDC181 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total CCDC181 protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.8mg/ml (varies by lot)
Sequence Length
1667
Applicable Applications for anti-CCDC181 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:200-1:1000
IHC: 1: 25-100
IHC: 1: 25-100
Immunogen
Synthetic protein corresponding to residues near the C terminal of human CCDC181
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.
SDS-Page
(Gel: 8%SDS-PAGE lysate: 40 ¦Œg, Lane 1-2: K562 cell and Mouse testis tissue lysates, Primary antibody: 46420£¨CCDC181 Antibody) at dilution 1/250 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds)
SDS-Page
(Gel: 8%SDS-PAGE lysate: 40 ¦Œg, Lane 1-2: K562 cell and Mouse testis tissue lysates, Primary antibody: 46420£¨CCDC181 Antibody) at dilution 1/250 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds)
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 46420(CCDC181 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 46420(CCDC181 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 46420(CCDC181 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 46420(CCDC181 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200))
Related Product Information for anti-CCDC181 antibody
CCDC181, also known as C1orf114, chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3, 000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf114 gene product has been provisionally designated C1orf114 pending further characterization.
Product Categories/Family for anti-CCDC181 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
60 kDa
NCBI Official Full Name
Homo sapiens chromosome 1 open reading frame 114, mRNA
NCBI Official Synonym Full Names
coiled-coil domain containing 181
NCBI Official Symbol
CCDC181
NCBI Official Synonym Symbols
C1orf114
NCBI Protein Information
coiled-coil domain-containing protein 181
UniProt Protein Name
Coiled-coil domain-containing protein 181
Protein Family
UniProt Gene Name
CCDC181
Uniprot Description
Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
Research Articles on CCDC181
Similar Products
Product Notes
The CCDC181 ccdc181 (Catalog #AAA9429567) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCDC181 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCDC181 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:200-1:1000 IHC: 1: 25-100. Researchers should empirically determine the suitability of the CCDC181 ccdc181 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCDC181, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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