Western Blot (WB)
(CBR4 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CBR4 antibody detected the CBR4 protein (arrow).)
Rabbit anti-Human CBR4 Polyclonal Antibody | anti-CBR4 antibody
CBR4 Antibody (C-term)
Gene Names
CBR4; SDR45C1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CBR4; Polyclonal Antibody; CBR4 Antibody (C-term); Carbonyl reductase family member 4; 1---; 3-oxoacyl-[acyl-carrier-protein] reductase; 111-; Quinone reductase CBR4; anti-CBR4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CBR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-205 amino acids from the C-terminal region of human CBR4.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
178-205
Sequence Length
237
Applicable Applications for anti-CBR4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(CBR4 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CBR4 antibody detected the CBR4 protein (arrow).)
Western Blot (WB)
(CBR4 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CBR4 antibody detected the CBR4 protein (arrow).)
Related Product Information for anti-CBR4 antibody
The heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
Product Categories/Family for anti-CBR4 antibody
References
Chen, Z., et al. FASEB J. 23(11):3682-3691(2009)
Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :
Endo, S., et al. Biochem. Biophys. Res. Commun. 377(4):1326-1330(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :
Endo, S., et al. Biochem. Biophys. Res. Commun. 377(4):1326-1330(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25301
NCBI Official Full Name
carbonyl reductase family member 4
NCBI Official Synonym Full Names
carbonyl reductase 4
NCBI Official Symbol
CBR4
NCBI Official Synonym Symbols
SDR45C1
NCBI Protein Information
carbonyl reductase family member 4
UniProt Protein Name
Carbonyl reductase family member 4
Protein Family
UniProt Gene Name
CBR4
UniProt Synonym Gene Names
SDR45C1
UniProt Entry Name
CBR4_HUMAN
Uniprot Description
CBR4: The heteroteramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.-.-.-; EC 1.1.1.-; Mitochondrial; Oxidoreductase
Chromosomal Location of Human Ortholog: 4q32.3
Cellular Component: mitochondrial matrix
Molecular Function: protein binding; NAD(P)H dehydrogenase (quinone) activity; NADPH dehydrogenase (quinone) activity; quinone binding
Biological Process: fatty acid biosynthetic process; protein homotetramerization
Research Articles on CBR4
Similar Products
Product Notes
The CBR4 cbr4 (Catalog #AAA9200844) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 178-205. The CBR4 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CBR4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the CBR4 cbr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CBR4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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