Rabbit anti-Mouse, Rat Catenin Polyclonal Antibody
Phospho Catenin antibody
Reactivity
Mouse, Rat
Applications
Western Blot
Purity
Phospho Catenin antibody was purified by immunoaffinity purification.
Synonyms
Catenin; Polyclonal Antibody; Phospho Catenin antibody; Polyclonal Phospho Catenin; Phospho beta Catenin; Anti-Phospho Catenin; Phospho-Catenin; anti-Catenin antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody recognizes 90 kDa phosphorylated beta-Catenin (Ser45) of human, mouse, and rat origin.
Purity/Purification
Phospho Catenin antibody was purified by immunoaffinity purification.
Form/Format
Supplied in PBS buffer containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Concentration
500 ug/ml (varies by lot)
Sequence Length
793
Applicable Applications for anti-Catenin antibody
Western Blot (WB)
Application Notes
WB: 0.5-4 ug/ml
Biological Significance
Catenin is one of the key downstream effectors in the Wnt signaling pathway. It has been implicated to play an important role in early embryonic development and tumorigenesis. Catenin can be destabilized by GSK 3 or other kinases by phosphorylating it at serines 33, 37, 45 and threonine 41. Mutations of these phosphorylation sites in catenin have been found in many tumor cell lines.
Cross-Reactivity
Human, Mouse, Rat
Immunogen
Phospho Catenin antibody was raised in Rabbit using synthetic phospho-peptide corresponding to residues surrounding Ser45 of human -Catenin as the immunogen.
Preparation and Storage
Store at -20 degree C. For long-term storage, aliquot and freeze at -70 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-Catenin antibody
Rabbit polyclonal Phospho beta Catenin antibody
Product Categories/Family for anti-Catenin antibody
NCBI and Uniprot Product Information
Similar Products
Product Notes
The Catenin (Catalog #AAA835839) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho Catenin antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Catenin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the Catenin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Catenin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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