Western Blot (WB)
(Western blot analysis of Catenin alpha 1/2 expression in MCF7 (A); A431 (B); SHSY5Y (C); PC12 (D) whole cell lysates.)
Rabbit Catenin Alpha 1/2 Polyclonal Antibody | anti-CTNNA2 antibody
Catenin Alpha 1/2 Antibody
Gene Names
Ctnna1; Catna1; AA517462; AI988031; 2010010M04Rik
Applications
Western Blot, Immunohistochemistry
Purity
Immunogen Affinity Chromatography
Synonyms
Catenin Alpha 1/2; Polyclonal Antibody; Catenin Alpha 1/2 Antibody; Purified Polyclonal Catenin alpha 1/2 Antibody; Polyclonal Catenin alpha 1/2 antibody; Anti-Catenin alpha 1/2 antibody; CTNNA1 antibody; Catenin alpha-1 antibody; Alpha E-catenin antibody; Cadherin-associated protein antibody; Renal carcinoma antigen NY-REN-13 antibody; CTNNA2 antibody; CAPR antibody; Catenin alpha-2 antibody; Alpha N-catenin antibody; Alpha-catenin-related protein antibody; anti-CTNNA2 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of Catenin alpha 1/2 protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
906
Applicable Applications for anti-CTNNA2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:1000
IHC: 1:100-1:200
IHC: 1:100-1:200
Immunogen
Catenin alpha 1/2 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Catenin alpha 1/2 as the immunogen
Cross-Reactivity
Mouse, Rat, Chicken, Pig
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of Catenin alpha 1/2 expression in MCF7 (A); A431 (B); SHSY5Y (C); PC12 (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Catenin alpha 1/2 expression in MCF7 (A); A431 (B); SHSY5Y (C); PC12 (D) whole cell lysates.)
Related Product Information for anti-CTNNA2 antibody
Catenin alpha 1/2 associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
Product Categories/Family for anti-CTNNA2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
catenin alpha-1
NCBI Official Synonym Full Names
catenin (cadherin associated protein), alpha 1
NCBI Official Symbol
Ctnna1
NCBI Official Synonym Symbols
Catna1; AA517462; AI988031; 2010010M04Rik
NCBI Protein Information
catenin alpha-1
UniProt Protein Name
Catenin alpha-1
Protein Family
UniProt Gene Name
Ctnna1
UniProt Synonym Gene Names
Catna1
Uniprot Description
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
Research Articles on CTNNA2
Similar Products
Product Notes
The CTNNA2 ctnna1 (Catalog #AAA5314231) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Catenin Alpha 1/2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:1000 IHC: 1:100-1:200. Researchers should empirically determine the suitability of the CTNNA2 ctnna1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Catenin Alpha 1/2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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