Western Blot (WB)
(CASS4 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CASS4 antibody detected the CASS4 protein (arrow).)
Rabbit anti-Human CASS4 Polyclonal Antibody | anti-CASS4 antibody
CASS4 Antibody (C-term)
Gene Names
CASS4; CAS4; HEFL; HEPL; C20orf32
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CASS4; Polyclonal Antibody; CASS4 Antibody (C-term); Cas scaffolding protein family member 4; HEF-like protein; HEF1-EFS-p130Cas-like protein; HEPL; C20orf32; HEFL; anti-CASS4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CASS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 610-639 amino acids from the C-terminal region of human CASS4.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
610-639
Sequence Length
349
Applicable Applications for anti-CASS4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(CASS4 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CASS4 antibody detected the CASS4 protein (arrow).)
Western Blot (WB)
(CASS4 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CASS4 antibody detected the CASS4 protein (arrow).)
Related Product Information for anti-CASS4 antibody
Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.
Product Categories/Family for anti-CASS4 antibody
References
Singh, M.K., et al. Mol. Biol. Cell 19(4):1627-1636(2008)
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Deloukas, P., et al. Nature 414(6866):865-871(2001)
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Deloukas, P., et al. Nature 414(6866):865-871(2001)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
87144
NCBI Official Full Name
cas scaffolding protein family member 4 isoform b
NCBI Official Synonym Full Names
Cas scaffolding protein family member 4
NCBI Official Symbol
CASS4
NCBI Official Synonym Symbols
CAS4; HEFL; HEPL; C20orf32
NCBI Protein Information
cas scaffolding protein family member 4
UniProt Protein Name
Cas scaffolding protein family member 4
Protein Family
UniProt Gene Name
CASS4
UniProt Synonym Gene Names
C20orf32; HEFL; HEPL
UniProt Entry Name
CASS4_HUMAN
Uniprot Description
HEFL: Docking protein that plays a role in tyrosine kinase- based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading. Belongs to the CAS family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 20q13.31
Cellular Component: focal adhesion; cytoskeleton; membrane; cytoplasm
Molecular Function: two-component sensor activity
Biological Process: two-component signal transduction system (phosphorelay); cell adhesion
Research Articles on CASS4
Similar Products
Product Notes
The CASS4 cass4 (Catalog #AAA9204111) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 610-639. The CASS4 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CASS4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the CASS4 cass4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CASS4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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