Knockout Validation
(Knockout Validation: Lane 1: Wild-type Raji cell lysate;;Lane 2: CASP1 knockout Raji cell lysate;;Predicted MW: 10,30,35,43,45kDa ;Observed MW: 42kDa;Primary Ab: 5ug/ml Rabbit Anti-Porcine CASP1 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;(#MBS2086047))
Rabbit anti-Pig Caspase 1 (CASP1) Polyclonal Antibody | anti-CASP1 antibody
PE-Linked Polyclonal Antibody to Caspase 1 (CASP1)
Gene Names
Casp1; Ice; Il1bc
Reactivity
Pig
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Synonyms
Caspase 1 (CASP1); Polyclonal Antibody; PE-Linked Polyclonal Antibody to Caspase 1 (CASP1); ICE; IL1BC; IL1-BC; P45; Interleukin 1 Beta Converting Enzyme; Apoptosis-Related Cysteine Peptidase; Interleukin-1 beta convertase; anti-CASP1 antibody
Host
Rabbit
Reactivity
Pig
Clonality
Polyclonal
Concentration
>=100ug/ml (varies by lot)
Applicable Applications for anti-CASP1 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
Immunogen
CASP1 (Asn120~Asp297)
Conjugation
PE
Cross Reactivity
Human, Pig
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2002145
Knockout Validation
(Knockout Validation: Lane 1: Wild-type Raji cell lysate;;Lane 2: CASP1 knockout Raji cell lysate;;Predicted MW: 10,30,35,43,45kDa ;Observed MW: 42kDa;Primary Ab: 5ug/ml Rabbit Anti-Porcine CASP1 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;(#MBS2086047))
Knockout Validation
(Knockout Validation: Lane 1: Wild-type Raji cell lysate;;Lane 2: CASP1 knockout Raji cell lysate;;Predicted MW: 10,30,35,43,45kDa ;Observed MW: 42kDa;Primary Ab: 5ug/ml Rabbit Anti-Porcine CASP1 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;(#MBS2086047))
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,576 Da
NCBI Official Full Name
caspase-1
NCBI Official Synonym Full Names
caspase 1
NCBI Official Symbol
Casp1
NCBI Official Synonym Symbols
Ice; Il1bc
NCBI Protein Information
caspase-1
UniProt Protein Name
Caspase-1
UniProt Gene Name
Casp1
UniProt Synonym Gene Names
Il1bc; Il1bce; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme
NCBI Description
apoptotic protease that may play a role in inflammation and apoptosis in male sex organs [RGD, Feb 2006]
Uniprot Description
CASP1: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis (By similarity)
Protein type: Apoptosis; EC 3.4.22.36; Protease
Research Articles on CASP1
Similar Products
Product Notes
The CASP1 casp1 (Catalog #AAA2056878) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PE-Linked Polyclonal Antibody to Caspase 1 (CASP1) reacts with Pig and may cross-react with other species as described in the data sheet. AAA Biotech's Caspase 1 (CASP1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the CASP1 casp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Caspase 1 (CASP1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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