Sheep Casein Kinase 1, delta Polyclonal Antibody | anti-CSNK1D antibody

Casein Kinase 1, delta

Cat. Num. AAA613331

• Gene Names: CSNK1D; HCKID
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: Casein Kinase 1; delta; Polyclonal Antibody; Anti -Casein Kinase 1; anti-CSNK1D antibody

• Host: Sheep
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human mouse, and rat Casein Kinase 1 delta. Does not cross-react with rhCK1 or rhCK1 ; reactivity with rhCK1 is unknown.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 1ml sterile 40-50% glycerol, PBS.

• Applicable Applications for anti-CSNK1D antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot., , Recommended Dilutions:, Western blot: 1ug/ml, Optimal dilutions to be determined by the researcher.
• Immunogen: E. coli-derived recombinant human CK1delta.
• Preparation and Storage: Lyophilized powder may be stored at -20 degree C. Reconstitute to nominal volume by adding sterile buffer. Aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-CSNK1D antibody

Casein Kinase 1 (CK1) represents a group of serine/threonine protein kinases that are present in all eukaryotic organisms. Human CK1 isoforms (a, 1, 2, 3, and) act as monomeric constitutively active enzymes that phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, and circadian rhythms. CK1 family members share a highly conserved kinase domain but differ in their variable N- and C-terminal domains. CK1 phosphorylates p53 as well as MDM2 and seems to play a principal role in coordinating the effects of these two key regulator proteins on cell growth and genome integrity.

Product Categories/Family for anti-CSNK1D antibody

Antibodies; Abs to Protein Kinases

NCBI and Uniprot Product Information

• NCBI GI #: 16041786
• NCBI GeneID: 1453
• UniProt Accession #: P48730; Q96KZ6; Q9BTN5; A2I2P2; Q59FJ7
• Molecular Weight: 47,330 Da
• NCBI Official Full Name: Casein kinase 1, delta
• NCBI Official Synonym Full Names: casein kinase 1, delta
• NCBI Official Symbol: CSNK1D
• NCBI Official Synonym Symbols: HCKID
• NCBI Protein Information: casein kinase I isoform delta; CKId; CKI-delta
• UniProt Protein Name: Casein kinase I isoform delta
• Protein Family: Casein kinase
• UniProt Gene Name: CSNK1D
• UniProt Entry Name: KC1D_HUMAN

NCBI Description

This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Uniprot Description

CK1D: an ubiquitous protein kinase of the CK1 family. Enriched at the centrosomes in interphase and at the spindle during mitosis. May play a role in cell cycle progression. Two splice variant isoforms have been described.

Protein type: EC 2.7.11.26; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Protein kinase, CK1; Kinase, protein; CK1 group; CK1 family

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: Golgi apparatus; centrosome; perinuclear region of cytoplasm; spindle microtubule; plasma membrane; spindle; cytosol; nucleus

Molecular Function: protein serine/threonine kinase activity; protein binding; tau-protein kinase activity; phosphoprotein binding; glycoprotein binding; peptide binding; ATP binding; protein kinase activity

Biological Process: Wnt receptor signaling pathway; organelle organization and biogenesis; endocytosis; spindle assembly; DNA repair; regulation of circadian rhythm; signal transduction; protein amino acid phosphorylation; regulation of cell shape; peptidyl-serine phosphorylation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein amino acid phosphorylation; mitotic cell cycle; circadian regulation of gene expression; G2/M transition of mitotic cell cycle

Disease: Advanced Sleep Phase Syndrome, Familial, 2