Rabbit anti-Human CARD6 Polyclonal Antibody | anti-CARD6 antibody

CARD6 Antibody

Cat. Num. AAA9413300

• Gene Names: CARD6; CINCIN1
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: CARD6; Polyclonal Antibody; CARD6 Antibody; Caspase recruitment domain-containing protein 6; anti-CARD6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total CARD6 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 1037

• Applicable Applications for anti-CARD6 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Western blotting: 1:500~1:3000; Immunohistochemistry: 1:50~1:100; Immunofluorescence: 1:100~1:500
• Immunogen Type: Peptide
• Immunogen Description: Synthesized peptide derived from human CARD6.
• Target Name: CARD6
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from HeLa cells, using CARD6 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CARD6 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of HeLa cells, using CARD6 antibody.)

Related Product Information for anti-CARD6 antibody

This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB.Frank C. Kischkel, J. Biol. Chem., Nov 2001; 276: 46639 - 46646.Daniela Sciaky, J. Immunol., Apr 2000; 164: 3806.Vassiliki Poulaki, Invest. Ophthalmol. Vis. Sci., Jan 2005; 46: 358 - 366.Lucia Ricci-Vitiani, J. Exp. Med., Nov 2004; 200: 1257 - 1266.

Product Categories/Family for anti-CARD6 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 16554564
• NCBI GeneID: 84674
• NCBI Accession #: NP_115976.2
• NCBI GenBank Nucleotide #: NM_032587.3
• UniProt Accession #: Q52LR2; Q9BX69
• Molecular Weight: 116,468 Da
• NCBI Official Full Name: caspase recruitment domain-containing protein 6
• NCBI Official Synonym Full Names: caspase recruitment domain family, member 6
• NCBI Official Symbol: CARD6
• NCBI Official Synonym Symbols: CINCIN1
• NCBI Protein Information: caspase recruitment domain-containing protein 6
• UniProt Protein Name: Caspase recruitment domain-containing protein 6
• Protein Family: Caspase recruitment domain-containing protein
• UniProt Gene Name: CARD6
• UniProt Entry Name: CARD6_HUMAN

NCBI Description

This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008]

Uniprot Description

CARD6: May be involved in apoptosis.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 5p13.1

Biological Process: regulation of apoptosis; apoptosis