Western Blot (WB)
(Western blot analysis of CAPZB Antibody (C-term) in mouse brain tissue lysates (35ug/lane). CAPZB (arrow) was detected using the purified Pab.)
Rabbit anti-Human CAPZB Polyclonal Antibody | anti-CAPZB antibody
CAPZB, CT (F-actin-capping Protein Subunit beta, CapZ beta)
Purified by ammonium sulfate precipitation.
Purified by ammonium sulfate precipitation.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Western Blot (WB)
(Western blot analysis of CAPZB Antibody (C-term) in mouse brain tissue lysates (35ug/lane). CAPZB (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of CAPZB Antibody (C-term) in mouse brain tissue lysates (35ug/lane). CAPZB (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of CAPZB (arrow) using rabbit polyclonal CAPZB Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CAPZB gene (Lane 2).)
Western Blot (WB)
(Western blot analysis of CAPZB (arrow) using rabbit polyclonal CAPZB Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CAPZB gene (Lane 2).)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Uniprot Description
CAPZB: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization. Belongs to the F-actin-capping protein beta subunit family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Actin-binding
Chromosomal Location of Human Ortholog: 1p36.1
Cellular Component: F-actin capping protein complex; sarcomere; cytoskeleton; actin filament; cytosol; actin cytoskeleton
Molecular Function: actin filament binding; actin binding
Biological Process: regulation of cell morphogenesis; cytoskeleton organization and biogenesis; barbed-end actin filament capping; cell motility; actin cytoskeleton organization and biogenesis; blood coagulation; negative regulation of filopodium formation
Research Articles on CAPZB
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Product Notes
The CAPZB capzb (Catalog #AAA628824) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAPZB, CT (F-actin-capping Protein Subunit beta, CapZ beta) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CAPZB can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100. Researchers should empirically determine the suitability of the CAPZB capzb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAPZB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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