Western Blot (WB)
(Western blot analysis of CAPS1 in rat brain tissue lysate with CAPS1 antibody at (A) 0.25 and (B) 0.5 ug/mL.)
Rabbit CAPS1 Polyclonal Antibody | anti-CAPS1 antibody
CAPS1 Antibody
Western Blot (WB)
(Western blot analysis of CAPS1 in rat brain tissue lysate with CAPS1 antibody at (A) 0.25 and (B) 0.5 ug/mL.)
Western Blot (WB)
(Western blot analysis of CAPS1 in rat brain tissue lysate with CAPS1 antibody at (A) 0.25 and (B) 0.5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of CAPS1 in human brain with CAPS1 antibody at 5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of CAPS1 in human brain with CAPS1 antibody at 5 ug/mL.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008]
Uniprot Description
CADPS: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates catecholamine loading of DCVs. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles by acting as a PtdIns(4,5)P2-binding protein that acts at prefusion step following ATP-dependent priming and participates in DCVs-membrane fusion. However, it may also participate in small clear synaptic vesicles (SVs) exocytosis and it is unclear whether its function is related to Ca(2+) triggering. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 3p14.2
Cellular Component: cytoplasmic vesicle membrane; synapse; cytosol; cell junction
Molecular Function: protein binding; metal ion binding; protein kinase binding; lipid binding
Biological Process: catecholamine secretion; protein transport; exocytosis; vesicle organization and biogenesis; synaptic vesicle priming
Research Articles on CAPS1
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Product Notes
The CAPS1 cadps (Catalog #AAA9401432) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAPS1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CAPS1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CAPS1 cadps for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAPS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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