Western Blot (WB)
(Western Blot analysis of CAPN5 expression in transfected 293T cell line by CAPN5 polyclonal antibody. Lane 1: CAPN5 transfected lysate (73.2kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human CAPN5 Polyclonal Antibody | anti-CAPN5 antibody
CAPN5 (Calpain-5, Calpain 5, Calpain htra-3, New Calpain 3, nCL-3, NCL3)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of CAPN5 expression in transfected 293T cell line by CAPN5 polyclonal antibody. Lane 1: CAPN5 transfected lysate (73.2kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of CAPN5 expression in transfected 293T cell line by CAPN5 polyclonal antibody. Lane 1: CAPN5 transfected lysate (73.2kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3. [provided by RefSeq, Jul 2008]
Uniprot Description
CAPN5: Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3. [provided by RefSeq, Jul 2008]
Protein type: Protease; EC 3.4.22.-
Chromosomal Location of Human Ortholog: 11q14
Cellular Component: cell surface; focal adhesion; cytoplasm
Molecular Function: calcium-dependent cysteine-type endopeptidase activity
Biological Process: signal transduction; proteolysis
Disease: Vitreoretinopathy, Neovascular Inflammatory
Research Articles on CAPN5
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Product Notes
The CAPN5 capn5 (Catalog #AAA6006064) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAPN5 (Calpain-5, Calpain 5, Calpain htra-3, New Calpain 3, nCL-3, NCL3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CAPN5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the CAPN5 capn5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MFSCVKPYED QNYSALRRDC RRRKVLFEDP LFPATDDSLY YKGTPGPAVR WKRPKGICED PRLFVDGISS HDLHQGQVGN CWFVAACSSL ASRESLWQKV IPDWKEQEWD PEKPNAYAGI FHFHFWRFGE WVDVVIDDRL PTVNNQLIYC HSNSRNEFWC ALVEKAYAKL AGCYQALDGG NTADALVDFT GGVSEPIDLT EGDFANDETK RNQLFERMLK VHSRGGLISA SIKAVTAADM EARLACGLVK GHAYAVTDVR KVRLGHGLLA FFKSEKLDMI RLRNPWGERE WNGPWSDTSE EWQKVSKSER EKMGVTVQDD GEFWMTFEDV CRYFTDIIKC RVINTSHLSI HKTWEEARLH GAWTLHEDPR QNRGGGCINH KDTFFQNPQY IFEVKKPEDE VLICIQQRPK RSTRREGKGE NLAIGFDIYK VEENRQYRMH SLQHKAASSI YINSRSVFLR TDQPEGRYVI IPTTFEPGHT GEFLLRVFTD VPSNCRELRL DEPPHTCWSS LCGYPQLVTQ VHVLGAAGLK DSPTGANSYV IIKCEGDKVR SAVQKGTSTP EYNVKGIFYR KKLSQPITVQ VWNHRVLKDE FLGQVHLKAD PDNLQALHTL HLRDRNSRQP SNLPGTVAVH ILSSTSLMAV. It is sometimes possible for the material contained within the vial of "CAPN5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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