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Immunohistochemistry (IHC) (Human Lung, Macrophages: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit CAPG / MCP Polyclonal Antibody | anti-CAPG antibody

Rabbit Polyclonal (IgG) to Human CAPG / MCP

Gene Names
CAPG; MCP; AFCP; HEL-S-66
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Purified
Synonyms
CAPG / MCP; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human CAPG / MCP; Anti-CAPG / MCP Antibody IHC-plus; CAPG; AFCP; Actin-regulatory protein CAP-G; Actin regulatory protein CAP-G; Gelsolin-like capping protein; MCP; Macrophage capping protein; Macrophage-capping protein; Human CAPG; anti-CAPG antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CAPG antibody detects endogenous levels of CAPG protein. Not tested with other proteins.
Purity/Purification
Purified
Form/Format
PBS, pH 7.4, 0.05% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
348
Applicable Applications for anti-CAPG antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:10000), IHC-P (2.5 ug/ml), WB (1:250)
Target Species
Human
Immunogen Description
Synthetic peptide conjugated to KLH
Immunogen Type
Synthetic peptide - KLH conjugated
Preparation and Storage
Store at -20 degree C for up to one year.

Immunohistochemistry (IHC)

(Human Lung, Macrophages: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Lung, Macrophages: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

( )

Western Blot (WB) ( )

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
822
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,857 Da
NCBI Official Full Name
macrophage-capping protein isoform 1
NCBI Official Synonym Full Names
capping protein (actin filament), gelsolin-like
NCBI Official Symbol
CAPG
NCBI Official Synonym Symbols
MCP; AFCP; HEL-S-66
NCBI Protein Information
macrophage-capping protein; macrophage capping protein; gelsolin-like capping protein; actin regulatory protein CAP-G; actin-regulatory protein CAP-G; epididymis secretory protein Li 66
UniProt Protein Name
Macrophage-capping protein
Protein Family
UniProt Gene Name
CAPG
UniProt Synonym Gene Names
AFCP; MCP
UniProt Entry Name
CAPG_HUMAN

NCBI Description

This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

CAPG: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Belongs to the villin/gelsolin family.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2p11.2

Cellular Component: F-actin capping protein complex; melanosome; nucleus

Molecular Function: actin binding

Biological Process: protein complex assembly; cell projection biogenesis; barbed-end actin filament capping

Research Articles on CAPG

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Product Notes

The CAPG capg (Catalog #AAA248016) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human CAPG / MCP reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CAPG / MCP can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA (1:10000), IHC-P (2.5 ug/ml), WB (1:250). Researchers should empirically determine the suitability of the CAPG capg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAPG / MCP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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