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Western Blot (WB) (Western Blot analysis of Hela and HepG2 cell using CAP1 Polyclonal Antibody at dilution of 1:250)

Rabbit CAP1 Polyclonal Antibody | anti-CAP1 antibody

CAP1 Polyclonal Antibody

Gene Names
Park7; Dj1; CAP1; DJ-1; SP22
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
CAP1; Polyclonal Antibody; CAP1 Polyclonal Antibody; CAP; CAP1-PEN; anti-CAP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.2mg/mL (varies by lot)
Sequence Length
189
Applicable Applications for anti-CAP1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:200-1:1000
IHC: 1:25-1:100
Immunogen
Recombinant protein of human CAP1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of Hela and HepG2 cell using CAP1 Polyclonal Antibody at dilution of 1:250)

Western Blot (WB) (Western Blot analysis of Hela and HepG2 cell using CAP1 Polyclonal Antibody at dilution of 1:250)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human skin using CAP1 Polyclonal Antibody at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human skin using CAP1 Polyclonal Antibody at dilution of 1:50)
Related Product Information for anti-CAP1 antibody
The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants have been identified.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
19,974 Da
NCBI Official Full Name
CAP1
NCBI Official Synonym Full Names
parkinson protein 7
NCBI Official Symbol
Park7
NCBI Official Synonym Symbols
Dj1; CAP1; DJ-1; SP22
NCBI Protein Information
protein DJ-1; Parkinson disease (autosomal recessive, early onset) 7; contraception-associated protein 1; fertility protein SP22; parkinson disease protein 7 homolog
UniProt Protein Name
Protein DJ-1
Protein Family
UniProt Gene Name
Park7
UniProt Synonym Gene Names
Cap1; Protein CAP1
UniProt Entry Name
PARK7_RAT

NCBI Description

displays a specific localization pattern to the anterior-ventral surface of the equatorial segment; may play a role in sperm-egg interactions and fertilization [RGD, Feb 2006]

Uniprot Description

DJ-1: associated with autosomal recessive early onset parkinsonism. Involved in the oxidative stress response. Three cysteines in DJ-1 may be oxidized to cysteine sulphonic acid in the cellular response to H2O2. Loss of DJ-1 function may lead to neurodegeneration.

Protein type: Nuclear receptor co-regulator; EC 3.4.-.-; Transcription regulation; Tumor suppressor

Cellular Component: PML body; mitochondrion; axon; endoplasmic reticulum; cytoplasm; plasma membrane; chromatin; nucleus; cytosol; mitochondrial respiratory chain complex I; lipid raft

Molecular Function: identical protein binding; oxidoreductase activity, acting on peroxide as acceptor; protein homodimerization activity; transcription coactivator activity; mercury ion binding; transcription factor binding; mRNA binding; peptidase activity; protein binding; enzyme binding; copper ion binding; peroxiredoxin activity; androgen receptor binding; cytokine binding; double-stranded DNA binding; glyoxalase III activity; kinase binding; superoxide dismutase copper chaperone activity; single-stranded DNA binding; receptor binding

Biological Process: synaptic transmission, dopaminergic; negative regulation of protein export from nucleus; adult locomotory behavior; protein deglycosylation; membrane hyperpolarization; proteolysis; glycolate biosynthetic process; positive regulation of interleukin-8 production; regulation of mitochondrial membrane potential; negative regulation of protein amino acid phosphorylation; single fertilization; regulation of neuron apoptosis; dopamine uptake; negative regulation of neuron apoptosis; inflammatory response; negative regulation of protein binding; response to drug; mitochondrion organization and biogenesis; protein stabilization; regulation of TRAIL receptor biosynthetic process; detoxification of copper ion; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of peptidyl-serine phosphorylation; negative regulation of protein sumoylation; methylglyoxal catabolic process to D-lactate; membrane depolarization; fertilization; response to hydrogen peroxide; detoxification of mercury ion; regulation of inflammatory response; negative regulation of ubiquitin-protein ligase activity; hydrogen peroxide metabolic process; lactate biosynthetic process; autophagy; negative regulation of protein kinase activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of protein ubiquitination; positive regulation of transcription factor activity; response to oxidative stress; negative regulation of apoptosis

Research Articles on CAP1

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Product Notes

The CAP1 park7 (Catalog #AAA2520068) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAP1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CAP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1:200-1:1000 IHC: 1:25-1:100. Researchers should empirically determine the suitability of the CAP1 park7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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