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Western Blot (WB) (Lane 1: Rat Brain Tissue Lysate, Lane 2: Rat Brain Tissue Lysate, Lane 3: Mouse Brain Tissue Lysate, Lane 4: Mouse Brain Tissue Lysate)

Rabbit CAMKII Polyclonal Antibody | anti-CAMKII antibody

CAMKII Antibody

Gene Names
Camk2a; CaMKII; R74975; mKIAA0968
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
CAMKII; Polyclonal Antibody; CAMKII Antibody; Affinity Purified Rabbit Polyclonal CAMKII Antibody; Polyclonal CAMKII antibody; Anti-CAMKII antibody; MGC15254 antibody; CAMKKB antibody; CAMKK2 antibody; CAMKK antibody; KIAA0787 antibody; Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 Beta antibody; anti-CAMKII antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Lyophilized Form
Sequence Length
478
Applicable Applications for anti-CAMKII antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Immunogen
CAMKII antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of human CAMKK2, identical to the related rat and Rabbit sequences, as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Lane 1: Rat Brain Tissue Lysate, Lane 2: Rat Brain Tissue Lysate, Lane 3: Mouse Brain Tissue Lysate, Lane 4: Mouse Brain Tissue Lysate)

Western Blot (WB) (Lane 1: Rat Brain Tissue Lysate, Lane 2: Rat Brain Tissue Lysate, Lane 3: Mouse Brain Tissue Lysate, Lane 4: Mouse Brain Tissue Lysate)
Related Product Information for anti-CAMKII antibody
CAMKK2 is a calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 seems to be involved in hippocampal activation of CREB1.
Product Categories/Family for anti-CAMKII antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 2
NCBI Official Synonym Full Names
calcium/calmodulin-dependent protein kinase II alpha
NCBI Official Symbol
Camk2a
NCBI Official Synonym Symbols
CaMKII; R74975; mKIAA0968
NCBI Protein Information
calcium/calmodulin-dependent protein kinase type II subunit alpha
UniProt Protein Name
Calcium/calmodulin-dependent protein kinase type II subunit alpha
UniProt Gene Name
Camk2a
UniProt Synonym Gene Names
CaM kinase II subunit alpha; CaMK-II subunit alpha
UniProt Entry Name
KCC2A_MOUSE

Uniprot Description

CAMK2A: a protein kinase of the CAMK2 family. A prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses that may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. The holoenzyme is composed of four different chains: alpha, beta, gamma, and delta. The different chains assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. May interact with BAALC, MPDZ, SYN1 and synGAP. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.7.11.17; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; CAMK group; CAMK2 family

Cellular Component: dendrite cytoplasm; mitochondrion; cell soma; membrane; axon; cytoplasm; dendrite; postsynaptic density; plasma membrane; synapse; cell junction; nucleus

Molecular Function: glutamate receptor binding; protein homodimerization activity; calmodulin-dependent protein kinase activity; nucleotide binding; GTPase activating protein binding; protein kinase activity; calmodulin binding; transferase activity; protein serine/threonine kinase activity; protein binding; transferase activity, transferring phosphorus-containing groups; kinase activity; ATP binding

Biological Process: peptidyl-serine phosphorylation; ionotropic glutamate receptor signaling pathway; protein amino acid autophosphorylation; calcium ion transport; regulation of neurotransmitter secretion; positive regulation of calcium ion transport; protein amino acid phosphorylation; phosphorylation; G1/S transition of mitotic cell cycle; activation of NF-kappaB transcription factor; regulation of neuronal synaptic plasticity

Research Articles on CAMKII

Similar Products

Product Notes

The CAMKII camk2a (Catalog #AAA5312809) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CAMKII can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the CAMKII camk2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAMKII, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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