Knockout Validation
(Knockout Validation: Lane 1: Wild-type HCT116 cell lysate; Lane 2: CAPN9 knockout HCT116 cell lysate; Predicted MW: 76,79kd Observed MW: 80kd Primary Ab: 1ug/ml Rabbit Anti-Human CAPN9 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
Rabbit anti-Human Calpain 9 (CAPN9) Polyclonal Antibody | anti-CAPN9 antibody
APC-Linked Polyclonal Antibody to Calpain 9 (CAPN9)
Knockout Validation
(Knockout Validation: Lane 1: Wild-type HCT116 cell lysate; Lane 2: CAPN9 knockout HCT116 cell lysate; Predicted MW: 76,79kd Observed MW: 80kd Primary Ab: 1ug/ml Rabbit Anti-Human CAPN9 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
Knockout Validation
(Knockout Validation: Lane 1: Wild-type HCT116 cell lysate; Lane 2: CAPN9 knockout HCT116 cell lysate; Predicted MW: 76,79kd Observed MW: 80kd Primary Ab: 1ug/ml Rabbit Anti-Human CAPN9 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
NCBI and Uniprot Product Information
NCBI Description
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
CAPN9: Calcium-regulated non-lysosomal thiol-protease. Belongs to the peptidase C2 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Calcium-binding; EC 3.4.22.-; Protease
Chromosomal Location of Human Ortholog: 1q42.2
Cellular Component: cytoplasm
Research Articles on CAPN9
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Product Notes
The CAPN9 capn9 (Catalog #AAA2069142) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APC-Linked Polyclonal Antibody to Calpain 9 (CAPN9) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Calpain 9 (CAPN9) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the CAPN9 capn9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calpain 9 (CAPN9), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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