Rabbit anti-Human CALNA3 Polyclonal Antibody | anti-CALNA3 antibody

CALNA3, CT (Calmodulin-dependent Calcineurin A Subunit gamma Isoform, Serine/Threonine-protein Phosphatase 2B Catalytic Subunit gamma Isoform, CAM-PRP Catalytic Subunit, Calcineurin, Testis-specific Catalytic Subunit, PPP3CC, CNA3) (HRP)

Cat. Num. AAA6466551

• Gene Names: PPP3CC; CNA3; CALNA3; PP2Bgamma
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Ammonium Sulfate Precipitation.
• Synonyms: CALNA3; Polyclonal Antibody; CT (Calmodulin-dependent Calcineurin A Subunit gamma Isoform; Serine/Threonine-protein Phosphatase 2B Catalytic Subunit gamma Isoform; CAM-PRP Catalytic Subunit; Calcineurin; Testis-specific Catalytic Subunit; PPP3CC; CNA3) (HRP); anti-CALNA3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human PPP3CC.
• Purity/Purification: Purified by Ammonium Sulfate Precipitation.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
• Sequence Length: 512

• Applicable Applications for anti-CALNA3 antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:50-1:100; ELISA: 1:1,000; WB: 1:100-1:500; Applications are based on unconjugated antibody.
• Immunogen: Synthetic peptide selected from the C-terminal region of human PPP3CC (KLH).
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)

Western Blot (WB)

(Western blot analysis of anti-PPP3CC Pab in A375cell line lysate.PPP3CC(arrow) was detected using the purified Pab.)

Product Categories/Family for anti-CALNA3 antibody

Antibodies; Enzymes; Phosphatase

References

1. Eastwood, S.L., et al., Biol. Psychiatry 57(7):702-710 (2005). 2. Gerber, D.J., et al., Proc. Natl. Acad. Sci. USA 100(15):8993-8998 (2003). 3. Bennasser, Y., et al., Virology 303(1):174-180 (2002). 4. Esau, C., et al., J. Exp. Med. 194(10):1449-1459 (2001). 5. Muramatsu, T., et al., Biochem. Biophys. Res. Commun. 188(1):265-271 (1992).

NCBI and Uniprot Product Information

• NCBI GI #: 21361290
• NCBI GeneID: 5533
• NCBI Accession #: NP_005596
• NCBI GenBank Nucleotide #: NP_005596.2
• UniProt Accession #: Q9BSS6; P48454
• Molecular Weight: 58.129
• NCBI Official Full Name: serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform 2
• NCBI Official Synonym Full Names: protein phosphatase 3 catalytic subunit gamma
• NCBI Official Symbol: PPP3CC
• NCBI Official Synonym Symbols: CNA3; CALNA3; PP2Bgamma
• NCBI Protein Information: serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

NCBI Description

Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]