Western Blot (WB)
(Western Blot analysis of hepg2 cells using Antibody diluted at 1000. Secondary antibody was diluted at 1:20000)
Rabbit Cactin Polyclonal Antibody | anti-CACTIN antibody
Cactin Rabbit pAb
ELISA: 1:10,000-20,000
Western Blot (WB)
(Western Blot analysis of hepg2 cells using Antibody diluted at 1000. Secondary antibody was diluted at 1:20000)
Western Blot (WB)
(Western Blot analysis of hepg2 cells using Antibody diluted at 1000. Secondary antibody was diluted at 1:20000)
NCBI and Uniprot Product Information
Uniprot Description
CACTIN: Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon- regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing. Belongs to the CACTIN family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Spliceosome; RNA splicing
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: protein binding
Biological Process: nuclear mRNA splicing, via spliceosome; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of protein amino acid phosphorylation; inhibition of NF-kappaB transcription factor; multicellular organismal development; negative regulation of toll-like receptor signaling pathway; negative regulation of interleukin-8 production; innate immune response; negative regulation of tumor necrosis factor production; negative regulation of interferon-beta production
Research Articles on CACTIN
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Product Notes
The CACTIN cactin (Catalog #AAA4755249) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cactin Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Cactin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-2000 ELISA: 1:10,000-20,000. Researchers should empirically determine the suitability of the CACTIN cactin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cactin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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