Western Blot (WB)
(Western Blot analysis of CACNB1 expression in transfected 293T cell line by CACNB1 polyclonal antibody. Lane 1: CACNB1 transfected lysate (65.7kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human CACNB1 Polyclonal Antibody | anti-Cacnb1 antibody
CACNB1 (Voltage-dependent L-type Calcium Channel Subunit beta-1, CAB1, Calcium Channel Voltage-dependent Subunit beta 1, CACNLB1)
Gene Names
Cacnb1; CAB1; Cchb1; Cchlb1
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
CACNB1; Polyclonal Antibody; CACNB1 (Voltage-dependent L-type Calcium Channel Subunit beta-1; CAB1; Calcium Channel Voltage-dependent Subunit beta 1; CACNLB1); Anti -CACNB1 (Voltage-dependent L-type Calcium Channel Subunit beta-1; anti-Cacnb1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CACNB1.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASMHEYPGELGQPPGLYPSSHPPGRAGTLRALSRQDTFDADTPGSRNSAYTELGDSCVDMETDPSEGPGLGDPAGGGTPPARQGSWEDEEEDYEEELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR
Applicable Applications for anti-Cacnb1 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Full length human CACNB1, aa1-598 (NP_000714.3).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of CACNB1 expression in transfected 293T cell line by CACNB1 polyclonal antibody. Lane 1: CACNB1 transfected lysate (65.7kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of CACNB1 expression in transfected 293T cell line by CACNB1 polyclonal antibody. Lane 1: CACNB1 transfected lysate (65.7kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-Cacnb1 antibody
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Product Categories/Family for anti-Cacnb1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
65,486 Da
NCBI Official Full Name
Cacnb1 protein
NCBI Official Synonym Full Names
calcium channel, voltage-dependent, beta 1 subunit
NCBI Official Symbol
Cacnb1
NCBI Official Synonym Symbols
CAB1; Cchb1; Cchlb1
NCBI Protein Information
voltage-dependent L-type calcium channel subunit beta-1; voltage-dependent calcium channel beta1 subunit; calcium channel voltage-dependent subunit beta 1
UniProt Protein Name
Voltage-dependent L-type calcium channel subunit beta-1
Protein Family
UniProt Gene Name
Cacnb1
UniProt Synonym Gene Names
Cacnlb1; CAB1
UniProt Entry Name
CACB1_MOUSE
Uniprot Description
Function: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting
By similarity.
Subunit structure: The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma
By similarity. Interacts with JSRP1. Interacts with RYR1. Ref.5 Ref.8
Subcellular location: Cell membrane › sarcolemma; Peripheral membrane protein; Cytoplasmic side
By similarity.
Sequence similarities: Belongs to the calcium channel beta subunit family.Contains 1 SH3 domain.
Research Articles on Cacnb1
Similar Products
Product Notes
The Cacnb1 cacnb1 (Catalog #AAA649581) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CACNB1 (Voltage-dependent L-type Calcium Channel Subunit beta-1, CAB1, Calcium Channel Voltage-dependent Subunit beta 1, CACNLB1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CACNB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the Cacnb1 cacnb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MVQKTSMSRG PYPPSQEIPM EVFDPSPQGK YSKRKGRFKR SDGSTSSDTT SNSFVRQGSA ESYTSRPSDS DVSLEEDREA LRKEAERQAL AQLEKAKTKP VAFAVRTNVG YNPSPGDEVP VQGVAITFEP KDFLHIKEKY NNDWWIGRLV KEGCEVGFIP SPVKLDSLRL LQEQKLRQNR LGSSKSGDNS SSSLGDVVTG TRRPTPPASA KQKQKSTEHV PPYDVVPSMR PIILVGPSLK GYEVTDMMQK ALFDFLKHRF DGRISITRVT ADISLAKRSV LNNPSKHIII ERSNTRSSLA EVQSEIERIF ELARTLQLVA LDADTINHPA QLSKTSLAPI IVYIKITSPK VLQRLIKSRG KSQSKHLNVQ IAASEKLAQC PPEMFDIILD ENQLEDACEH LAEYLEAYWK ATHPPSSTPP NPLLNRTMAT AALAASPAPV SNLQGPYLAS GDQPLERATG EHASMHEYPG ELGQPPGLYP SSHPPGRAGT LRALSRQDTF DADTPGSRNS AYTELGDSCV DMETDPSEGP GLGDPAGGGT PPARQGSWED EEEDYEEELT DNRNRGRNKA RYCAEGGGPV LGRNKNELEG WGRGVYIR. It is sometimes possible for the material contained within the vial of "CACNB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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