Western Blot (WB)
((0. 03ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat CACNA2D1 Polyclonal Antibody | anti-CACNA2D1 antibody
Goat anti-CACNA2D1 Antibody
Western Blot: Approx 140kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 123kDa according to NP_000713.2). Recommended concentration: 0. 03-0.1ug/ml. Customer found it not suitable on Mouse and Rat protein.
Western Blot (WB)
((0. 03ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((0. 03ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014]
Uniprot Description
CACNA2D1: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling. Belongs to the calcium channel subunit alpha-2/delta family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Channel, calcium
Chromosomal Location of Human Ortholog: 7q21-q22
Cellular Component: plasma membrane; sarcoplasmic reticulum; voltage-gated calcium channel complex
Molecular Function: metal ion binding; voltage-gated calcium channel activity
Biological Process: calcium ion transport; regulation of calcium ion transport
Research Articles on CACNA2D1
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Product Notes
The CACNA2D1 cacna2d1 (Catalog #AAA420998) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-CACNA2D1 Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's CACNA2D1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Approx 140kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 123kDa according to NP_000713.2). Recommended concentration: 0. 03-0.1ug/ml. Customer found it not suitable on Mouse and Rat protein. Researchers should empirically determine the suitability of the CACNA2D1 cacna2d1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: QEIFNKYNKD KKVR. It is sometimes possible for the material contained within the vial of "CACNA2D1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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