Rabbit anti-Human, Mouse CABYR Polyclonal Antibody | anti-CABYR antibody

CABYR Rabbit Polyclonal

Cat. Num. AAA767402

• Gene Names: CABYR; CT88; FSP2; CBP86; FSP-2; CABYRa; CABYRc; CABYRe; CABYRc/d
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: CABYR; Polyclonal Antibody; CABYR Rabbit Polyclonal; anti-CABYR antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 221

• Applicable Applications for anti-CABYR antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: Calcium binding tyrosine-(Y)-phosphorylation regulated
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue slide using MBS767402 (CABYR Antibody) at dilution of 1:200)

Western Blot (WB)

(human testis tissue were subjected to SDS PAGE followed by western blot with MBS767402 (CABYR antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 24797118
• NCBI GeneID: 26256
• NCBI Accession #: NP_722454.1
• NCBI GenBank Nucleotide #: NM_153770.2
• Molecular Weight: 30,936 Da
• NCBI Official Full Name: calcium-binding tyrosine phosphorylation-regulated protein isoform e
• NCBI Official Synonym Full Names: calcium binding tyrosine phosphorylation regulated
• NCBI Official Symbol: CABYR
• NCBI Official Synonym Symbols: CT88; FSP2; CBP86; FSP-2; CABYRa; CABYRc; CABYRe; CABYRc/d
• NCBI Protein Information: calcium-binding tyrosine phosphorylation-regulated protein
• UniProt Protein Name: Calcium-binding tyrosine phosphorylation-regulated protein
• Protein Family: Calcium-binding tyrosine phosphorylation-regulated protein
• UniProt Gene Name: CABYR
• UniProt Synonym Gene Names: CBP86; FSP2; CT88; FSP-2
• UniProt Entry Name: CABYR_HUMAN

NCBI Description

To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2013]

Uniprot Description

CABYR: May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Calcium-binding; Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 18q11.2

Cellular Component: cytoplasm; nucleus

Molecular Function: calcium ion binding; protein heterodimerization activity