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Testing Data

Rabbit CA11 Polyclonal Antibody | anti-CA11 antibody

CA11 Antibody

Gene Names
CA11; CARPX1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
CA11; Polyclonal Antibody; CA11 Antibody; CARP2; CARPX1; anti-CA11 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Sequence Length
328
Applicable Applications for anti-CA11 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:200-1:2000
IHC: 1:20-1:200
Immunogen
Fusion protein of CA11
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54669 / sc-54742 / sc-54744 / sc-67333
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles

Testing Data

Testing Data

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
770
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,238 Da
NCBI Official Full Name
carbonic anhydrase-related protein 11
NCBI Official Synonym Full Names
carbonic anhydrase XI
NCBI Official Symbol
CA11
NCBI Official Synonym Symbols
CARPX1
NCBI Protein Information
carbonic anhydrase-related protein 11; CA-RP II; CA-XI; CARP XI; CARP-2; carbonic anhydrase-related protein 2; carbonic anhydrase-related protein XI
UniProt Protein Name
Carbonic anhydrase-related protein 11
UniProt Gene Name
CA11
UniProt Synonym Gene Names
CARP2; CA-XI; CARP XI; CA-RP II; CARP-2
UniProt Entry Name
CAH11_HUMAN

NCBI Description

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq, Jul 2008]

Uniprot Description

CA11: Does not have a catalytic activity. Belongs to the alpha-carbonic anhydrase family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: basolateral plasma membrane; extracellular region

Molecular Function: carbonate dehydratase activity

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Product Notes

The CA11 ca11 (Catalog #AAA2523923) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CA11 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CA11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1:200-1:2000 IHC: 1:20-1:200. Researchers should empirically determine the suitability of the CA11 ca11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CA11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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