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Western Blot (WB) (C6orf70 Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the C6orf70 antibody detected the C6orf70 protein (arrow).)

Rabbit C6orf70 Polyclonal Antibody | anti-ERMARD antibody

C6orf70 Antibody (Center)

Gene Names
ERMARD; PVNH6; C6orf70; dJ266L20.3
Reactivity
Human (Predicted Reactivity: Monkey)
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
C6orf70; Polyclonal Antibody; C6orf70 Antibody (Center); Endoplasmic reticulum membrane-associated RNA degradation protein; ER membrane-associated RNA degradation protein; ERMARD; anti-ERMARD antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Monkey)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This C6orf70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the Central region of human C6orf70.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
346-375
Sequence Length
552
Applicable Applications for anti-ERMARD antibody
Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(C6orf70 Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the C6orf70 antibody detected the C6orf70 protein (arrow).)

Western Blot (WB) (C6orf70 Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the C6orf70 antibody detected the C6orf70 protein (arrow).)

Immunohistochemistry (IHC)

(C6orf70 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the C6orf70 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (C6orf70 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the C6orf70 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(C6orf70 Antibody (Center) flow cytometric analysis of A2058 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (C6orf70 Antibody (Center) flow cytometric analysis of A2058 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Product Categories/Family for anti-ERMARD antibody
References
Wistow, G., et al. Mol. Vis. 8, 205-220 (2002) :

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
77788
NCBI Official Full Name
endoplasmic reticulum membrane-associated RNA degradation protein isoform 2
NCBI Official Synonym Full Names
ER membrane-associated RNA degradation
NCBI Official Symbol
ERMARD
NCBI Official Synonym Symbols
PVNH6; C6orf70; dJ266L20.3
NCBI Protein Information
endoplasmic reticulum membrane-associated RNA degradation protein
UniProt Protein Name
Endoplasmic reticulum membrane-associated RNA degradation protein
UniProt Gene Name
ERMARD
UniProt Synonym Gene Names
C6orf70; ER membrane-associated RNA degradation protein
UniProt Entry Name
EMARD_HUMAN

NCBI Description

The protein encoded by this gene contains 2 transmembrane domains near the C-terminus and is localized in the endoplasmic reticulum. Knockout of this gene in developing rat brain showed that it may be involved in neuronal migration. Mutations in this gene are associated with periventricular nodular heterotopia-6 (PVNH6). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]

Uniprot Description

ERMARD: 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Biological Process: multicellular organismal development

Disease: Periventricular Nodular Heterotopia 6

Research Articles on ERMARD

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Product Notes

The ERMARD ermard (Catalog #AAA9204788) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 346-375. The C6orf70 Antibody (Center) reacts with Human (Predicted Reactivity: Monkey) and may cross-react with other species as described in the data sheet. AAA Biotech's C6orf70 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the ERMARD ermard for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C6orf70, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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