Immunohistochemistry (IHC)
(Anti-C3AR / C3a Receptor antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.25 ug/ml.)
Rabbit C3AR / C3a Receptor Polyclonal Antibody | anti-C3AR1 antibody
Rabbit Polyclonal to Human C3AR / C3a Receptor
Gene Names
C3AR1; AZ3B; C3AR; HNFAG09
Reactivity
Gibbon, Gorilla, Human, OrangutanPredicted Reactivity: Monkey, Mouse, Hamster, Horse (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
C3AR / C3a Receptor; Polyclonal Antibody; Rabbit Polyclonal to Human C3AR / C3a Receptor; Anti-C3AR / C3a Receptor Antibody (C-Terminus) IHC-plus; C3AR1; AZ3B; C3AR; C3R1; C3a receptor; C3a-R; HNFAG09; Anaphylatoxin c3a receptor; C3a anaphylatoxin receptor; Human C3AR; C3a Receptor; anti-C3AR1 antibody
Host
Rabbit
Reactivity
Gibbon, Gorilla, Human, Orangutan
Predicted Reactivity: Monkey, Mouse, Hamster, Horse (at least 90% immunogen sequence identity)
Predicted Reactivity: Monkey, Mouse, Hamster, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human C3a Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
0.31 mg/ml (varies by lot)
Sequence Length
482
Applicable Applications for anti-C3AR1 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (1.25 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from C-terminus of human C3a Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Marmoset (100%); Monkey, Mouse, Hamster, Elephant, Horse (95%); Rat, Bat (89%).
Immunogen Type
Synthetic peptide
Immunogen
C3AR / C3a Receptor antibody was raised against synthetic 19 amino acid peptide from C-terminus of human C3a Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Marmoset (100%); Monkey, Mouse, Hamster, Elephant, Horse (95%); Rat, Bat (89%); Bovine, Rabbit (84%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Immunohistochemistry (IHC)
(Anti-C3AR / C3a Receptor antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.25 ug/ml.)
Immunohistochemistry (IHC)
(Anti-C3AR / C3a Receptor antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.25 ug/ml.)
Immunohistochemistry (IHC)
(Anti-C3AR / C3a Receptor antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.25 ug/ml.)
Immunohistochemistry (IHC)
(Anti-C3AR / C3a Receptor antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.25 ug/ml.)
Related Product Information for anti-C3AR1 antibody
The C3a Anaphylatoxin Receptor mediates the effects of the inflammatory mediator anaphylatoxin C3a, which is released during complement activation. This receptor stimulates chemotaxis, granule enzyme release, and superoxide anion production. It also regulates glial cell activation, may be involved in the pathogenesis of asthma, and may promote cell repair.
Product Categories/Family for anti-C3AR1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,864 Da
NCBI Official Full Name
C3a anaphylatoxin chemotactic receptor
NCBI Official Synonym Full Names
complement component 3a receptor 1
NCBI Official Symbol
C3AR1
NCBI Official Synonym Symbols
AZ3B; C3AR; HNFAG09
NCBI Protein Information
C3a anaphylatoxin chemotactic receptor; C3a-R; complement component 3 receptor 1
UniProt Protein Name
C3a anaphylatoxin chemotactic receptor
Protein Family
UniProt Gene Name
C3AR1
UniProt Synonym Gene Names
AZ3B; C3R1; HNFAG09; C3AR; C3a-R
UniProt Entry Name
C3AR_HUMAN
Uniprot Description
C3aR: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 12p13.31
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; C3a anaphylatoxin receptor activity; complement component C3a receptor activity; phosphoinositide phospholipase C activity
Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; positive regulation of angiogenesis; metabolic process; blood circulation; complement receptor mediated signaling pathway; chemotaxis; inflammatory response
Research Articles on C3AR1
Similar Products
Product Notes
The C3AR1 c3ar1 (Catalog #AAA247181) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human C3AR / C3a Receptor reacts with Gibbon, Gorilla, Human, Orangutan Predicted Reactivity: Monkey, Mouse, Hamster, Horse (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's C3AR / C3a Receptor can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (1.25 ug/ml). Researchers should empirically determine the suitability of the C3AR1 c3ar1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C3AR / C3a Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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