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Western Blot (WB) (Western blot analysis of extracts of mouse kidney, using C1GALT1 antibody.)

Rabbit anti-Human, Mouse C1GALT1 Polyclonal Antibody | anti-C1GALT1 antibody

C1GALT1 Polyclonal Antibody

Gene Names
C1GALT1; C1GALT; T-synthase
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purification
Synonyms
C1GALT1; Polyclonal Antibody; C1GALT1 Polyclonal Antibody; C1GALT; T-synthase; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; anti-C1GALT1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 50% glycerol, pH7.4
Applicable Applications for anti-C1GALT1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:100
Immunogen
Recombinant fusion protein of human C1GALT1 (NP_064541.1).
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of mouse kidney, using C1GALT1 antibody.)

Western Blot (WB) (Western blot analysis of extracts of mouse kidney, using C1GALT1 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung using C1GALT1 antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lung using C1GALT1 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human stomach using C1GALT1 antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human stomach using C1GALT1 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded mouse lung using C1GALT1 antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse lung using C1GALT1 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded mouse kidney using C1GALT1 antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse kidney using C1GALT1 antibody.)
Related Product Information for anti-C1GALT1 antibody
The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.
Product Categories/Family for anti-C1GALT1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,935 Da
NCBI Official Full Name
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
NCBI Official Synonym Full Names
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
NCBI Official Symbol
C1GALT1
NCBI Official Synonym Symbols
C1GALT; T-synthase
NCBI Protein Information
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; B3Gal-T8; core 1 O-glycan T-synthase; core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1; core 1 beta3-Gal-T1; core 1 synthase, glycoprotein-N-acetylgalact
UniProt Protein Name
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
UniProt Gene Name
C1GALT1
UniProt Synonym Gene Names
Beta-1,3-galactosyltransferase; C1GalT1; Core 1 beta3-Gal-T1
UniProt Entry Name
C1GLT_HUMAN

NCBI Description

The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.[provided by RefSeq, Sep 2010]

Uniprot Description

C1GALT1: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development. Belongs to the glycosyltransferase 31 family. Beta3- Gal-T subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 2.4.1.122; Glycan Metabolism - O-glycan biosynthesis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7p21.3

Cellular Component: Golgi membrane; integral to membrane

Molecular Function: protein binding; metal ion binding; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; angiogenesis; kidney development; post-translational protein modification

Research Articles on C1GALT1

Similar Products

Product Notes

The C1GALT1 c1galt1 (Catalog #AAA9431697) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The C1GALT1 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's C1GALT1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:100. Researchers should empirically determine the suitability of the C1GALT1 c1galt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C1GALT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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