Rabbit anti-Human, Mouse C10orf63 Polyclonal Antibody | anti-C10orf63 antibody

C10orf63, ID (ENKUR, C10orf63, Enkurin) (Biotin)

Cat. Num. AAA6279409

• Gene Names: ENKUR; CFAP106; C10orf63
• Reactivity: Human, Mouse
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: C10orf63; Polyclonal Antibody; ID (ENKUR; Enkurin) (Biotin); ENKUR; Enkurin; anti-C10orf63 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
• Sequence Length: 256

• Applicable Applications for anti-C10orf63 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: C10orf63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-137 amino acids from the Central region of human C10orf63.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(C10orf63 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the C10orf63 antibody detected the C10orf63 protein (arrow).)

Western Blot (WB)

(C10orf63 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the C10orf63 antibody detected the C10orf63 protein (arrow).)

Related Product Information for anti-C10orf63 antibody

Enkurin interacts with transient receptor potential canonical (TRPC) cation channels (see TRPC1; MIM 602343) and functions as an adaptor protein, tethering signal transduction proteins to TRPC channels (Sutton et al., 2004 [PubMed 15385169]).

Product Categories/Family for anti-C10orf63 antibody

Antibodies; KIAA; orf

References

Beech, D.J. Handb Exp Pharmacol 179, 109-123 (2007): Sutton, K.A., et al. Dev. Biol. 274(2):426-435(2004). Deloukas, P., et al. Nature 429(6990):375-381(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 21450721
• NCBI GeneID: 219670
• NCBI Accession #: NP_659447.1
• NCBI GenBank Nucleotide #: NP_659447.1
• UniProt Accession #: Q8TC29
• NCBI Official Full Name: enkurin isoform 1
• NCBI Official Synonym Full Names: enkurin, TRPC channel interacting protein
• NCBI Official Symbol: ENKUR
• NCBI Official Synonym Symbols: CFAP106; C10orf63
• NCBI Protein Information: enkurin
• UniProt Protein Name: Enkurin
• UniProt Gene Name: ENKUR
• UniProt Synonym Gene Names: C10orf63

NCBI Description

This gene encodes a protein that interacts with calmodulin and several transient receptor potential canonical cation channel proteins. The encoded protein may function as an adaptor to localize signal transduction machinery to calcium channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

Uniprot Description

Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel.