Rabbit BTAF1 Polyclonal Antibody | anti-BTAF1 antibody

BTAF1 Antibody

Cat. Num. AAA2526981

• Gene Names: BTAF1; MOT1; TAF172; TAFII170; TAF(II)170
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, Immunoprecipitation
• Purity: Antigen affinity purification
• Synonyms: BTAF1; Polyclonal Antibody; BTAF1 Antibody; MOT1; TAF172; TAFII170; TAF(II)170; anti-BTAF1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen affinity purification
• Concentration: 1mg/mL (varies by lot)
• Sequence Length: 420

• Applicable Applications for anti-BTAF1 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), CHIP
• Immunogen: Recombinant protein of human BTAF1
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Preparation and Storage: Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using BTAF1 antibody.)

Related Product Information for anti-BTAF1 antibody

This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters.

NCBI and Uniprot Product Information

• NCBI GI #: 211828489
• NCBI GeneID: 9044
• Molecular Weight: 76,419 Da
• NCBI Official Full Name: BTAF1 protein, partial
• NCBI Official Synonym Full Names: BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
• NCBI Official Symbol: BTAF1
• NCBI Official Synonym Symbols: MOT1; TAF172; TAFII170; TAF(II)170
• NCBI Protein Information: TATA-binding protein-associated factor 172; ATP-dependent helicase BTAF1; B-TFIID transcription factor-associated 170 kDa subunit; BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae); TBP-associated factor 172
• UniProt Protein Name: TATA-binding protein-associated factor 172
• Protein Family: TATA-binding protein-associated factor
• UniProt Gene Name: BTAF1
• UniProt Synonym Gene Names: TAF172; TAF-172
• UniProt Entry Name: BTAF1_HUMAN

NCBI Description

This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters. [provided by RefSeq, Sep 2011]

Uniprot Description

TAF172: Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner. Associates with TBP to form B-TFIID. Binds DRAP1. Belongs to the SNF2/RAD54 helicase family.

Protein type: EC 3.6.1.-; Transcription initiation complex; EC 3.6.4.-; Helicase

Chromosomal Location of Human Ortholog: 10q22-q23

Cellular Component: nucleus

Molecular Function: DNA binding; helicase activity; transcription factor activity; ATP binding

Biological Process: metabolic process; negative regulation of transcription, DNA-dependent