Western Blot (WB)
(Western blot analysis of 4T1 using p-Bmx (Y566) antibody.)
Rabbit anti-Human, Mouse Bmx Polyclonal Antibody | anti-Bmx antibody
Bmx (Phospho-Tyr566) Polyclonal Antibody
Immunohistochemistry: 1:100 - 1:300
ELISA: 1:10000
Not yet tested in other applications
Western Blot (WB)
(Western blot analysis of 4T1 using p-Bmx (Y566) antibody.)
Western Blot (WB)
(Western blot analysis of 4T1 using p-Bmx (Y566) antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009]
Uniprot Description
Etk: a tyrosine kinase of the Tec family. Activity is required for IL6-induced differentiation. May play a role in the growth and differentiation of hematopoietic cells. May be involved in signal transduction in endocardial and arterial endothelial cells.
Protein type: Protein kinase, tyrosine (non-receptor); EC 2.7.10.2; Kinase, protein; Protein kinase, TK; TK group; Tec family
Chromosomal Location of Human Ortholog: Xp22.2
Cellular Component: extrinsic to internal side of plasma membrane; cytosol
Molecular Function: protein binding; signal transducer activity; metal ion binding; protein-tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; ATP binding; receptor binding
Biological Process: adaptive immune response; apoptosis; protein amino acid autophosphorylation; signal transduction; protein amino acid phosphorylation; T cell receptor signaling pathway; regulation of cell proliferation; B cell receptor signaling pathway; innate immune response; mesoderm development; cell differentiation; cell adhesion; transmembrane receptor protein tyrosine kinase signaling pathway; cell structure disassembly during apoptosis
Research Articles on Bmx
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Product Notes
The Bmx bmx (Catalog #AAA9407419) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bmx (Phospho-Tyr566) Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Bmx can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). Western blotting: 1:500 - 1:2000 Immunohistochemistry: 1:100 - 1:300 ELISA: 1:10000 Not yet tested in other applications. Researchers should empirically determine the suitability of the Bmx bmx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bmx, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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