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Western Blot (WB)

Rabbit BMP-7 Polyclonal Antibody | anti-BMP-7 antibody

BMP-7 Antibody

Gene Names
BMP7; OP-1
Reactivity
Human. Not yet tested in other species.
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
BMP-7; Polyclonal Antibody; BMP-7 Antibody; anti-BMP-7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human. Not yet tested in other species.
Clonality
Polyclonal
Form/Format
Lyophilized anti-BMP-7 antibody purified by peptide affinity column containing 1% BSA and 0.02% NaN3
Applicable Applications for anti-BMP-7 antibody
Peptide ELISA, Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Peptide ELISA titer: 1:1,000-1:10000
WB analysis: 1:200-1:1,000
IHC: 1:50-200

Optimal dilutions/concentrations should be determined by end user.
Host Note
Rabbit polyclonal BMP-7 antibody was raised against a peptide from near the C-terminal residues of human BMP-7 protein.
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20°C after reconstitution. Avoid repeated freeze/defrost cycles.

Western Blot (WB)

Western Blot (WB)

Immunohistochemisry (IHC)

Immunohistochemisry (IHC)
References
(1)Sengle, G., Ono, R.N., Lyons, K.M., et al. A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7. J. Mol. Biol. 381 (4), 1025-1039 (2008).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
655
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
bone morphogenetic protein 7 preproprotein
NCBI Official Synonym Full Names
bone morphogenetic protein 7
NCBI Official Symbol
BMP7
NCBI Official Synonym Symbols
OP-1
NCBI Protein Information
bone morphogenetic protein 7
UniProt Protein Name
Bone morphogenetic protein 7
UniProt Gene Name
BMP7
UniProt Synonym Gene Names
OP1; BMP-7; OP-1

NCBI Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016]

Uniprot Description

Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.

Research Articles on BMP-7

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Product Notes

The BMP-7 bmp7 (Catalog #AAA853509) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BMP-7 Antibody reacts with Human. Not yet tested in other species. and may cross-react with other species as described in the data sheet. AAA Biotech's BMP-7 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA, Western Blot (WB), Immunohistochemistry (IHC). Peptide ELISA titer: 1:1,000-1:10000 WB analysis: 1:200-1:1,000 IHC: 1:50-200 Optimal dilutions/concentrations should be determined by end user. Researchers should empirically determine the suitability of the BMP-7 bmp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BMP-7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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