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Rabbit BMP 10 Polyclonal Antibody | anti-BMP 10 antibody

BMP 10 antibody

Applications
Western Blot
Purity
BMP 10 antibody was purified by affinity purification.
Synonyms
BMP 10; Polyclonal Antibody; BMP 10 antibody; Polyclonal BMP 10; Anti-BMP 10; Bone morphogenetic protein 10; BMP -10; BMP-10; anti-BMP 10 antibody
Ordering
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
BMP 10 antibody was purified by affinity purification.
Form/Format
Supplied in PBS buffer, pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Concentration
500 ug/ml (varies by lot)
Sequence Length
421
Applicable Applications for anti-BMP 10 antibody
Western Blot (WB)
Application Notes
WB: 0.5-4 ug/ml
Biological Significance
BMPs belong to the TGF superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP 14 is a principal inhibitor of cartilage development and is predominantly expressed in long bone during human embryonic development.
Cross-Reactivity
Human
Immunogen
BMP 10 antibody was raised in Rabbit using E Coli expressed human BMP-10 as the immunogen.
Preparation and Storage
Store at -20 degree C. For long-term storage, aliquot and freeze at -70 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-BMP 10 antibody
Rabbit polyclonal BMP 10 antibody
Product Categories/Family for anti-BMP 10 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,767 Da
NCBI Official Full Name
bone morphogenetic protein 10
NCBI Official Synonym Full Names
bone morphogenetic protein 10
NCBI Official Symbol
Bmp10
NCBI Protein Information
bone morphogenetic protein 10
UniProt Protein Name
Bone morphogenetic protein 10
UniProt Gene Name
Bmp10
UniProt Synonym Gene Names
BMP-10
UniProt Entry Name
BMP10_RAT

Uniprot Description

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines ().

Research Articles on BMP 10

Similar Products

Product Notes

The BMP 10 bmp10 (Catalog #AAA837342) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BMP 10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the BMP 10 bmp10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BMP 10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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