Western Blot (WB)
(Western blotAll lanes: Biogenesis of lysosome-related organelles complex 1 subunit 1 antibody at 2ug/mlLane 1: EC109 whole cell lysateLane 2: 293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilutionPredicted band size: 18,15 kDaObserved band size: 75 kDa)
Rabbit anti-Human Biogenesis of lysosome-related organelles complex 1 subunit 1 Polyclonal Antibody | anti-BLOC1S1 antibody
Rabbit anti-human Biogenesis of lysosome-related organelles complex 1 subunit 1 polyclonal Antibody
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Western Blot (WB)
(Western blotAll lanes: Biogenesis of lysosome-related organelles complex 1 subunit 1 antibody at 2ug/mlLane 1: EC109 whole cell lysateLane 2: 293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilutionPredicted band size: 18,15 kDaObserved band size: 75 kDa)
Western Blot (WB)
(Western blotAll lanes: Biogenesis of lysosome-related organelles complex 1 subunit 1 antibody at 2ug/mlLane 1: EC109 whole cell lysateLane 2: 293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilutionPredicted band size: 18,15 kDaObserved band size: 75 kDa)
Immunofluorescence (IF)
(Immunofluorescent analysis of HepG2 cells using MBS719940 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of HepG2 cells using MBS719940 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS719940 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS719940 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis tissue using MBS719940 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis tissue using MBS719940 at dilution of 1:100)
NCBI and Uniprot Product Information
NCBI Description
BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004 [PubMed 15102850]).[supplied by OMIM, Mar 2008]
Uniprot Description
BLOC1S1: May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5A1 AND NDUFA9. May also be involved in the biogenesis of specialized organelles of the endosomal-lysosomal system. Belongs to the BLOC1S1 family. 2 isoforms of the human protein are produced by alternative initiation.
Protein type: Nuclear receptor co-regulator; Vesicle
Chromosomal Location of Human Ortholog: 12q13-q14
Cellular Component: cytosol; extracellular space; lysosomal membrane; mitochondrial intermembrane space; mitochondrial matrix
Molecular Function: protein binding
Biological Process: aerobic respiration; anterograde axon cargo transport; anterograde synaptic vesicle transport; endosome transport; melanosome organization and biogenesis; neurite development; peptidyl-lysine acetylation; platelet dense granule organization and biogenesis; post-Golgi vesicle-mediated transport
Research Articles on BLOC1S1
Similar Products
Product Notes
The BLOC1S1 bloc1s1 (Catalog #AAA719940) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Biogenesis of lysosome-related organelles complex 1 subunit 1 polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Biogenesis of lysosome-related organelles complex 1 subunit 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the BLOC1S1 bloc1s1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Biogenesis of lysosome-related organelles complex 1 subunit 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
