Western Blot (WB)
(Western Blot analysis of BTC expression in transfected 293T cell line by BTC polyclonal antibody. Lane 1: BTC transfected lysate (19.7kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human Betacellulin Polyclonal Antibody | anti-BTC antibody
Betacellulin (BTC, Probetacellulin) (PE)
Western Blot (WB)
(Western Blot analysis of BTC expression in transfected 293T cell line by BTC polyclonal antibody. Lane 1: BTC transfected lysate (19.7kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of BTC expression in transfected 293T cell line by BTC polyclonal antibody. Lane 1: BTC transfected lysate (19.7kD). Lane 2: Non-transfected lysate.)
Testing Data
(Proximity Ligation Analysis (PLA) of protein-protein interactions between BTC and ERBB2. HeLa cells were stained with BTC rabbit purified polyclonal 1:1200 and ERBB2 mouse monoclonal antibody 1:50. Signals were detected by 30 Detection Kit 613 (red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex.)
Testing Data
(Proximity Ligation Analysis (PLA) of protein-protein interactions between BTC and ERBB2. HeLa cells were stained with BTC rabbit purified polyclonal 1:1200 and ERBB2 mouse monoclonal antibody 1:50. Signals were detected by 30 Detection Kit 613 (red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. [provided by RefSeq, Jul 2008]
Uniprot Description
BTC: Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
Protein type: Membrane protein, integral; Cell cycle regulation; Ligand, receptor tyrosine kinase
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: extracellular space; extracellular region; integral to membrane; plasma membrane
Molecular Function: protein binding; growth factor activity; epidermal growth factor receptor binding
Biological Process: epidermal growth factor receptor signaling pathway; positive regulation of fibroblast proliferation; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; positive regulation of mitosis; positive regulation of cell proliferation; innate immune response; positive regulation of cell differentiation; negative regulation of apoptosis
Research Articles on BTC
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Product Notes
The BTC btc (Catalog #AAA6371507) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Betacellulin (BTC, Probetacellulin) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Betacellulin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the BTC btc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Betacellulin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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