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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using beta Catenin antibody (Ser33))

Rabbit beta Catenin Polyclonal Antibody | anti-CTNNB antibody

beta Catenin Antibody (Ser33)

Gene Names
CTNNB1; EVR7; CTNNB; MRD19; NEDSDV; armadillo
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
beta Catenin; Polyclonal Antibody; beta Catenin Antibody (Ser33); Rabbit Polyclonal beta Catenin Antibody (Ser33); Polyclonal beta Catenin antibody; Anti-beta Catenin antibody; Beta-catenin antibody; catenin (cadherin-associated protein) beta 1 88kDa antibody; Catenin beta-1 antibody; CTNB1 antibody; CTNNB antibody; CTNNB1 antibody; DKFZp686D02253 antibody; FLJ25606 antibody; FLJ37923 antibody; anti-CTNNB antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
beta Catenin antibody (Ser33) detects endogenous levels of beta Catenin only when phosphorylated at serine 33
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
781
Applicable Applications for anti-CTNNB antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:1000
IHC: 1:50-1:100
Immunogen
beta Catenin antibody was raised in Rabbit using a synthesized phosphopeptide derived from human beta Catenin around the phosphorylation site of serine 33 (L-D-SP-G-I) as the immunogen.
Cross-Reactivity
Mouse, Rat
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using beta Catenin antibody (Ser33))

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using beta Catenin antibody (Ser33))

Western Blot (WB)

(Western blot analysis of extracts from SW 626 cells, untreated or treated with Calyculin A (50nM, 30min), using beta-Catenin antibody and beta Catenin antibody (Ser33) (Lanes 3 and 4))

Western Blot (WB) (Western blot analysis of extracts from SW 626 cells, untreated or treated with Calyculin A (50nM, 30min), using beta-Catenin antibody and beta Catenin antibody (Ser33) (Lanes 3 and 4))
Related Product Information for anti-CTNNB antibody
beta Catenino anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.
Product Categories/Family for anti-CTNNB antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Official Full Name
beta catenin
NCBI Official Synonym Full Names
catenin beta 1
NCBI Official Symbol
CTNNB1
NCBI Official Synonym Symbols
EVR7; CTNNB; MRD19; NEDSDV; armadillo
NCBI Protein Information
catenin beta-1

NCBI Description

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

Research Articles on CTNNB

Similar Products

Product Notes

The CTNNB (Catalog #AAA5313644) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's beta Catenin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:1000 IHC: 1:50-1:100. Researchers should empirically determine the suitability of the CTNNB for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "beta Catenin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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