Western Blot (WB)
(Western blot analysis of Beta-3 Adrenergic Receptor expression in HEK293T (A), Hela (B), HepG2 (C), A2780 (D), mouse kidney (E), rat liver (F) whole cell lysates.)
Beta-3 Adrenergic Receptor Polyclonal Antibody | anti-ADRB3 antibody
Anti-Beta-3 Adrenergic Receptor Antibody
Upon delivery aliquot and store at -20°C for one year.
Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of Beta-3 Adrenergic Receptor expression in HEK293T (A), Hela (B), HepG2 (C), A2780 (D), mouse kidney (E), rat liver (F) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Beta-3 Adrenergic Receptor expression in HEK293T (A), Hela (B), HepG2 (C), A2780 (D), mouse kidney (E), rat liver (F) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. [provided by RefSeq, Feb 2009]
Uniprot Description
ADRB3: Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1
Chromosomal Location of Human Ortholog: 8p12
Cellular Component: integral to plasma membrane; plasma membrane; nucleus; receptor complex
Molecular Function: beta3-adrenergic receptor activity; protein binding; protein homodimerization activity; beta-3 adrenergic receptor binding; norepinephrine binding; epinephrine binding; beta-adrenergic receptor activity
Biological Process: arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway; receptor-mediated endocytosis; diet induced thermogenesis; generation of precursor metabolites and energy; negative regulation of multicellular organism growth; eating behavior; adenylate cyclase activation; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; response to antibiotic; G-protein signaling, coupled to cyclic nucleotide second messenger; positive regulation of MAPKKK cascade; heat generation; carbohydrate metabolic process; brown fat cell differentiation; energy reserve metabolic process; response to cold; norepinephrine-epinephrine vasodilation involved in regulation of systemic arterial blood pressure; aging
Disease: Obesity
Research Articles on ADRB3
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Product Notes
The ADRB3 adrb3 (Catalog #AAA8220053) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Beta-3 Adrenergic Receptor Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Beta-3 Adrenergic Receptor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the ADRB3 adrb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Beta-3 Adrenergic Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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