Western Blot (WB)
(Western Blot: Sample: Recombinant b4GALNT2, Human.)
Rabbit anti-Human Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 Polyclonal Antibody | anti-b4GALNT2 antibody
Polyclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2)
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Recombinant b4GALNT2, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant b4GALNT2, Human.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:HumanTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:HumanTissue))
NCBI and Uniprot Product Information
NCBI Description
B4GALNT2 catalyzes the last step in the biosynthesis of the human Sd(a) antigen through the addition of an N-acetylgalactosamine residue via a beta-1,4 linkage to a subterminal galactose residue substituted with an alpha-2,3-linked sialic acid. B4GALNT2 also catalyzes the last step in the biosynthesis of the Cad antigen (Montiel et al., 2003 [PubMed 12678917]).[supplied by OMIM, Mar 2008]
Uniprot Description
B4GALNT2: Involved in the synthesis of the Sd(a) antigen (Sia- alpha2,3-[GalNAc-beta1,4]Gal-beta1,4-GlcNAc), a carbohydrate determinant expressed on erythrocytes, the colonic mucosa and other tissues. Transfers a beta-1,4-linked GalNAc to the galactose residue of an alpha-2,3-sialylated chain. Belongs to the glycosyltransferase 2 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.4.1.-; Membrane protein, integral; Transferase
Chromosomal Location of Human Ortholog: 17q21.32
Cellular Component: Golgi membrane; integral component of membrane; integral to Golgi membrane
Molecular Function: acetylgalactosaminyltransferase activity
Biological Process: lipid glycosylation; negative regulation of cell-cell adhesion; protein N-linked glycosylation via asparagine; UDP-N-acetylgalactosamine metabolic process; UDP-N-acetylglucosamine metabolic process
Research Articles on b4GALNT2
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Product Notes
The b4GALNT2 b4galnt2 (Catalog #AAA2026752) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/ml Immunocytochemistry in formalin fixed cells: 5-20ug/ml Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml Immunohistochemistry in paraffin section: 5-20ug/ml Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the b4GALNT2 b4galnt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Beta-1,4-N-Acetyl Galactosaminyl Transferase 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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