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Western blot (Western blot analysis of 1) Mouse Brain Tissue, 2) Rat Brain Tissue using BEST2 Polyclonal Antibody. Secondary antibody was diluted at 1:20000.)

Rabbit Bestrophin-2 Polyclonal Antibody | anti-BEST2 antibody

Bestrophin-2 Rabbit pAb

Gene Names
BEST2; VMD2L1
Reactivity
Human, Rat, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Purified
Synonyms
Bestrophin-2; Polyclonal Antibody; Bestrophin-2 Rabbit pAb; BEST 2 antibody; FLJ20132 antibody; Vitelliform macular dystrophy 2 homolog antibody; anti-BEST2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified
Form/Format
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Sequence Length
509
Applicable Applications for anti-BEST2 antibody
Western blot (WB), Immunohistochemistry-paraffin (IHC-P)
Application Notes
WB: 1: 500-1000
IHC: 1: 200-500
Immunogen
Synthetic Peptide of BEST2
Target
The antibody detects endogenous BEST2 protein.
Mark
Unconjugated
Cellular Localization
Cell Membrane, Membrane
Sequence similarity
Belongs to the bestrophin family.
Preparation and Storage
Store at -20 degree C.

Western blot

(Western blot analysis of 1) Mouse Brain Tissue, 2) Rat Brain Tissue using BEST2 Polyclonal Antibody. Secondary antibody was diluted at 1:20000.)

Western blot (Western blot analysis of 1) Mouse Brain Tissue, 2) Rat Brain Tissue using BEST2 Polyclonal Antibody. Secondary antibody was diluted at 1:20000.)

Immunohistochemical (IHC)

(Immunohistochemical analysis of paraffinembedded Rat Brain Tissue using BEST2 Polyclonal Antibody.)

Immunohistochemical (IHC) (Immunohistochemical analysis of paraffinembedded Rat Brain Tissue using BEST2 Polyclonal Antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50kDa
NCBI Official Full Name
bestrophin-2
NCBI Official Synonym Full Names
bestrophin 2
NCBI Official Symbol
BEST2
NCBI Official Synonym Symbols
VMD2L1
NCBI Protein Information
bestrophin-2
UniProt Protein Name
Bestrophin-2
Protein Family
UniProt Gene Name
BEST2
UniProt Synonym Gene Names
VMD2L1
UniProt Entry Name
BEST2_HUMAN

NCBI Description

This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008]

Uniprot Description

BEST2: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. Belongs to the bestrophin family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, ion channel

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: plasma membrane; cilium

Molecular Function: chloride channel activity

Biological Process: membrane depolarization; sensory perception of smell

Research Articles on BEST2

Similar Products

Product Notes

The BEST2 best2 (Catalog #AAA8542023) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bestrophin-2 Rabbit pAb reacts with Human, Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Bestrophin-2 can be used in a range of immunoassay formats including, but not limited to, Western blot (WB), Immunohistochemistry-paraffin (IHC-P). WB: 1: 500-1000 IHC: 1: 200-500. Researchers should empirically determine the suitability of the BEST2 best2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bestrophin-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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