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Western Blot (WB) (Western blot analysis of BCAS3 (arrow) using rabbit polyclonal BCAS3 Antibody (C-term) (RB13419). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the BCAS3 gene (Lane 2) (Origene Technologies).)

Rabbit anti-Human BCAS3 Polyclonal Antibody | anti-BCAS3 antibody

BCAS3, CT (Breast Carcinoma-amplified Sequence 3, GAOB1, Maab1 Protein, BCAS3)

Gene Names
BCAS3; MAAB; GAOB1; MGC4973; FLJ20128; DKFZp686O1527
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified
Purified by ammonium sulfate precipitation.
Synonyms
BCAS3; Polyclonal Antibody; CT (Breast Carcinoma-amplified Sequence 3; GAOB1; Maab1 Protein; BCAS3); Anti -BCAS3; anti-BCAS3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human BCAS3.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Applicable Applications for anti-BCAS3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunogen
Synthetic peptide selected from the C-terminal region of human BCAS3 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of BCAS3 (arrow) using rabbit polyclonal BCAS3 Antibody (C-term) (RB13419). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the BCAS3 gene (Lane 2) (Origene Technologies).)

Western Blot (WB) (Western blot analysis of BCAS3 (arrow) using rabbit polyclonal BCAS3 Antibody (C-term) (RB13419). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the BCAS3 gene (Lane 2) (Origene Technologies).)
Related Product Information for anti-BCAS3 antibody
BCAS3 is physically associated with histone H3 and histone acetyltransferase complex protein P/CAF (p300/CBP-associated factor) and possesses histone acetyltransferase activity. In breast cancer, several chromosomal sites frequently undergo amplification, implicating the location of genes important for tumor development and progression.
Product Categories/Family for anti-BCAS3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
101,237 Da
NCBI Official Full Name
breast carcinoma-amplified sequence 3 isoform 1
NCBI Official Synonym Full Names
breast carcinoma amplified sequence 3
NCBI Official Symbol
BCAS3
NCBI Official Synonym Symbols
MAAB; GAOB1; MGC4973; FLJ20128; DKFZp686O1527
NCBI Protein Information
breast carcinoma-amplified sequence 3; protein Maab1; BCAS4/BCAS3 fusion; metastasis associated antigen of breast cancer; breast carcinoma amplified sequence 4/3 fusion protein
UniProt Protein Name
Breast carcinoma-amplified sequence 3
UniProt Gene Name
BCAS3
UniProt Entry Name
BCAS3_HUMAN

Uniprot Description

BCAS3: A chromosomal aberration involving BCAS3 has been found in some breast carcinoma cell lines. Translocation t(17;20)(q23;q13) with BCAS4. Belongs to the WD repeat BCAS3 family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Oncoprotein

Chromosomal Location of Human Ortholog: 17q23

Cellular Component: intermediate filament cytoskeleton; cytoplasmic microtubule; leading edge; cytoplasm; nucleus

Molecular Function: histone acetyltransferase binding; protein binding; histone binding; beta-tubulin binding; chromatin binding; transcription factor binding; nuclear hormone receptor binding

Biological Process: positive regulation of filopodium formation; vesicle-mediated transport; positive regulation of catalytic activity; response to starvation; microtubule organizing center organization and biogenesis; transcription, DNA-dependent; negative regulation of focal adhesion formation; positive regulation of transcription from RNA polymerase II promoter; lumen formation; angiogenesis; Golgi organization and biogenesis

Research Articles on BCAS3

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Product Notes

The BCAS3 bcas3 (Catalog #AAA624748) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCAS3, CT (Breast Carcinoma-amplified Sequence 3, GAOB1, Maab1 Protein, BCAS3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BCAS3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100. Researchers should empirically determine the suitability of the BCAS3 bcas3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCAS3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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