Rabbit anti-Human BATF2 Polyclonal Antibody | anti-BATF2 antibody

BATF2, NT (BATF2, Basic leucine zipper transcriptional factor ATF-like 2, Suppressor of AP-1 regulated by IFN) (FITC)

Cat. Num. AAA6277672

• Gene Names: BATF2; SARI
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: BATF2; Polyclonal Antibody; NT (BATF2; Basic leucine zipper transcriptional factor ATF-like 2; Suppressor of AP-1 regulated by IFN) (FITC); Suppressor of AP-1 regulated by IFN; anti-BATF2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-BATF2 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: BATF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the N-terminal region of human BATF2.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(BATF2 Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the BATF2 antibody detected the BATF2 protein (arrow).)

Related Product Information for anti-BATF2 antibody

MGC20410 belongs to the bZIP family. It contains one bZIP domain. There are two isoforms.

Product Categories/Family for anti-BATF2 antibody

Antibodies; Transcription Factors

References

Dash, R., et al. Oncogene 29(31):4412-4423(2010). Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009). Su, Z.Z., et al. Proc. Natl. Acad. Sci. U.S.A. 105(52):20906-20911(2008). Lim, J., et al. Cell 125(4):801-814(2006).

NCBI and Uniprot Product Information

• NCBI GI #: 45238854
• NCBI GeneID: 116071
• NCBI Accession #: NP_612465.3
• NCBI GenBank Nucleotide #: NM_138456.3
• UniProt Accession #: Q8N1L9; Q8NAF4; Q8NAL8; Q96EH4; D9IC56
• Molecular Weight: 19,503 Da
• NCBI Official Full Name: basic leucine zipper transcriptional factor ATF-like 2 isoform 1
• NCBI Official Synonym Full Names: basic leucine zipper ATF-like transcription factor 2
• NCBI Official Symbol: BATF2
• NCBI Official Synonym Symbols: SARI
• NCBI Protein Information: basic leucine zipper transcriptional factor ATF-like 2
• UniProt Protein Name: Basic leucine zipper transcriptional factor ATF-like 2
• Protein Family: Basic leucine zipper transcriptional factor
• UniProt Gene Name: BATF2
• UniProt Synonym Gene Names: B-ATF-2; SARI

Uniprot Description

AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8+ thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (). Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.