Rabbit BART Polyclonal Antibody | anti-ARL2BP antibody

Anti-BART Antibody

Cat. Num. AAA8248139

• Gene Names: ARL2BP; BART; RP66; BART1
• Reactivity: Human, Mouse, Rat, Bovine, Monkey
• Applications: Western Blot
• Purity: The antibody was purified by affinity chromatography.
• Synonyms: BART; Polyclonal Antibody; Anti-BART Antibody; BART1; ADP-ribosylation factor-like protein 2-binding protein; ARF-like 2-binding protein; ARL2-binding protein; Binder of ARF2 protein 1; anti-ARL2BP antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat, Bovine, Monkey
• Clonality: Polyclonal
• Specificity: Recognizes endogenous levels of BART protein.
• Purity/Purification: The antibody was purified by affinity chromatography.
• Form/Format: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
• Sequence Length: 163

• Applicable Applications for anti-ARL2BP antibody: Western Blot (WB)
• Application Notes: WB: 1/500 - 1/2000
• Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BART. The exact sequence is proprietary.
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of BART expression in Jurkat (A), A549 (B), PC12 (C) whole cell lysates.)

Related Product Information for anti-ARL2BP antibody

Rabbit polyclonal antibody to BART

NCBI and Uniprot Product Information

• NCBI GI #: 6912268
• NCBI GeneID: 23568
• NCBI Accession #: NP_036238.1
• NCBI GenBank Nucleotide #: NM_012106.3
• UniProt Accession #: Q9Y2Y0; Q504R0; B3KQJ5
• Molecular Weight: 17,711 Da
• NCBI Official Full Name: ADP-ribosylation factor-like protein 2-binding protein
• NCBI Official Synonym Full Names: ADP ribosylation factor like GTPase 2 binding protein
• NCBI Official Symbol: ARL2BP
• NCBI Official Synonym Symbols: BART; RP66; BART1
• NCBI Protein Information: ADP-ribosylation factor-like protein 2-binding protein
• UniProt Protein Name: ADP-ribosylation factor-like protein 2-binding protein
• Protein Family: Barttin
• UniProt Gene Name: ARL2BP
• UniProt Synonym Gene Names: BART; BART1; ARF-like 2-binding protein; ARL2-binding protein
• UniProt Entry Name: AR2BP_HUMAN

NCBI Description

ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]

Uniprot Description

ARL2BP: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. Belongs to the ARL2BP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.; Mitochondrial

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: centrosome; cytosol; midbody; mitochondrial intermembrane space; mitochondrial matrix

Molecular Function: GTPase regulator activity; protein binding; transcription coactivator activity

Biological Process: maintenance of protein localization in nucleus; positive regulation of tyrosine phosphorylation of Stat3 protein; regulation of insulin secretion; signal transduction

Disease: Retinitis Pigmentosa With Or Without Situs Inversus