Rabbit anti-Human B7H6 Polyclonal Antibody | anti-B7H6 antibody

B7H6, CT (NCR3LG1, B7H6, Natural cytotoxicity triggering receptor 3 ligand 1, B7 homolog 6) (Azide free) (HRP)

Cat. Num. AAA6277254

• Gene Names: NCR3LG1; B7H6; B7-H6; DKFZp686O24166
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: B7H6; Polyclonal Antibody; CT (NCR3LG1; Natural cytotoxicity triggering receptor 3 ligand 1; B7 homolog 6) (Azide free) (HRP); NCR3LG1; B7 homolog 6; anti-B7H6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human B7H6.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-B7H6 antibody: Western Blot (WB)
• Application Notes: WB: 1:1000; Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 389-415 in the C-terminal region of human B7H6, UniProt Accession #NP_001189368.1; Q68D85
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis using MBS647769 in Hela cell line lysates (35ug/lane) This demonstrates that MBS647769 detected the B7H6 protein (arrow).)

Western Blot (WB)

(Western Blot analysis using MBS647769 (1:1000) in K562 cell line lysate (20ug). A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.)

Product Categories/Family for anti-B7H6 antibody

Antibodies; Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 320461732
• NCBI GeneID: 374383
• NCBI Accession #: NP_001189368.1
• NCBI GenBank Nucleotide #: NM_001202439.2
• UniProt Accession #: Q68D85; Q7Z3M6
• Molecular Weight: 80 kDa
• NCBI Official Full Name: natural cytotoxicity triggering receptor 3 ligand 1
• NCBI Official Synonym Full Names: natural killer cell cytotoxicity receptor 3 ligand 1
• NCBI Official Symbol: NCR3LG1
• NCBI Official Synonym Symbols: B7H6; B7-H6; DKFZp686O24166
• NCBI Protein Information: natural cytotoxicity triggering receptor 3 ligand 1
• UniProt Protein Name: Natural cytotoxicity triggering receptor 3 ligand 1
• UniProt Gene Name: NCR3LG1
• UniProt Synonym Gene Names: B7H6; B7-H6

NCBI Description

B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]

Uniprot Description

B7-H6: Triggers NCR3-dependent natural killer cell activation.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: plasma membrane

Biological Process: regulation of immune response