Rabbit anti-Human B3GNT3 Polyclonal Antibody | anti-B3GNT3 antibody
B3GNT3 Antibody
IHC: 1:50-1:200
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking. [provided by RefSeq, Jul 2008]
Uniprot Description
B3GNT3: Has a beta-1,3-N-acetylglucosaminyltransferase activity for type 2 oligosaccharides. Belongs to the glycosyltransferase 31 family.
Protein type: EC 2.4.1.146; Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Transferase
Chromosomal Location of Human Ortholog: 19p13.1
Cellular Component: Golgi membrane; integral to plasma membrane
Molecular Function: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity; galactosyltransferase activity
Biological Process: keratan sulfate metabolic process; protein amino acid O-linked glycosylation; poly-N-acetyllactosamine biosynthetic process; cellular protein metabolic process; glycosaminoglycan metabolic process; O-glycan processing; carbohydrate metabolic process; keratan sulfate biosynthetic process; pathogenesis; post-translational protein modification
Research Articles on B3GNT3
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Product Notes
The B3GNT3 b3gnt3 (Catalog #AAA2522178) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The B3GNT3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's B3GNT3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:5000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the B3GNT3 b3gnt3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "B3GNT3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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