Western Blot (WB)
(Western blot analysis of extracts from HepG2 cells, Jurkat cells, MCF-7 cells and HUVEC cells, using B3GALTL antibody.)
Rabbit anti-Human B3GALTL Polyclonal Antibody | anti-B3GALTL antibody
B3GALTL Antibody
Immunohistochemistry: 1:50~1:100
Western Blot (WB)
(Western blot analysis of extracts from HepG2 cells, Jurkat cells, MCF-7 cells and HUVEC cells, using B3GALTL antibody.)
Western Blot (WB)
(Western blot analysis of extracts from HepG2 cells, Jurkat cells, MCF-7 cells and HUVEC cells, using B3GALTL antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using B3GALTL antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using B3GALTL antibody.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).[provided by RefSeq, Mar 2009]
Uniprot Description
B3GALTL: O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan. Defects in B3GALTL are the cause of Peters-plus syndrome (PpS). PpS is an autosomal recessive disorder characterized by anterior eye-chamber abnormalities, disproportionate short stature, developmental delay, characteristic craniofacial features, cleft lip and/or palate. Belongs to the glycosyltransferase 31 family.
Protein type: EC 2.4.1.-; Membrane protein, integral; Transferase
Chromosomal Location of Human Ortholog: 13q12.3
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: transferase activity, transferring glycosyl groups
Biological Process: fucose metabolic process; protein amino acid O-linked glycosylation; cellular protein metabolic process; post-translational protein modification
Disease: Peters-plus Syndrome
Research Articles on B3GALTL
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Product Notes
The B3GALTL b3galtl (Catalog #AAA9407398) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The B3GALTL Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's B3GALTL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the B3GALTL b3galtl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "B3GALTL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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