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Western Blot (WB) (Western blot analysis AWAT2 using HepG2 whole cell lysates)

Rabbit anti-Human, Mouse AWAT2 Polyclonal Antibody | anti-AWAT2 antibody

AWAT2 Antibody

Gene Names
AWAT2; WS; DC4; ARAT; MFAT; DGAT2L4
Reactivity
Human, Mouse
Applications
Western Blot
Synonyms
AWAT2; Polyclonal Antibody; AWAT2 Antibody; ARAT; DGAT2L4; HWS; MFAT; Wax synthase; DC4; HDC4; WS; anti-AWAT2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
AWAT2 Antibody detects endogenous levels of total AWAT2
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
333
Applicable Applications for anti-AWAT2 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000-3000
Immunogen
A synthesized peptide derived from human AWAT2
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis AWAT2 using HepG2 whole cell lysates)

Western Blot (WB) (Western blot analysis AWAT2 using HepG2 whole cell lysates)
Product Categories/Family for anti-AWAT2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,094 Da
NCBI Official Full Name
acyl-CoA wax alcohol acyltransferase 2
NCBI Official Synonym Full Names
acyl-CoA wax alcohol acyltransferase 2
NCBI Official Symbol
AWAT2
NCBI Official Synonym Symbols
WS; DC4; ARAT; MFAT; DGAT2L4
NCBI Protein Information
acyl-CoA wax alcohol acyltransferase 2
UniProt Protein Name
Acyl-CoA wax alcohol acyltransferase 2
UniProt Gene Name
AWAT2
UniProt Synonym Gene Names
DC4; DGAT2L4; MFAT; WS; ARAT; Retinol O-fatty-acyltransferase; hDC4; hWS
UniProt Entry Name
AWAT2_HUMAN

NCBI Description

This gene encodes an enzyme belonging to the diacylglycerol acyltransferase family. This enzyme produces wax esters by the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids. It functions in lipid metabolism in the skin, mostly in undifferentiated peripheral sebocytes. This enzyme may also have acyl-CoA:retinol acyltransferase activities, where it catalyzes the synthesis of diacylglycerols and retinyl esters. [provided by RefSeq, May 2010]

Uniprot Description

DGAT2L4: Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. May also have 2-acylglycerol O-acyltransferase (MGAT) and acyl- CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters; however this activity is unclear in vivo. Belongs to the diacylglycerol acyltransferase family.

Protein type: Cofactor and Vitamin Metabolism - retinol; EC 2.3.1.75; EC 2.3.1.76; Lipid Metabolism - glycerolipid; Membrane protein, integral; Membrane protein, multi-pass; Transferase

Chromosomal Location of Human Ortholog: Xq13.1

Cellular Component: endoplasmic reticulum membrane

Molecular Function: 2-acylglycerol O-acyltransferase activity; long-chain-alcohol O-fatty-acyltransferase activity; retinol O-fatty-acyltransferase activity

Biological Process: cellular lipid metabolic process; wax biosynthetic process

Research Articles on AWAT2

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Product Notes

The AWAT2 awat2 (Catalog #AAA9419138) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AWAT2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AWAT2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the AWAT2 awat2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AWAT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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