Chicken ATP7A Polyclonal Antibody | anti-ATP7A antibody

ATP7A (ATPase, Copper Transporting, alpha Polypeptide)

Cat. Num. AAA615268

• Gene Names: ATP7A; MK; MNK; DSMAX; SMAX3; FLJ17790
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: ATP7A; Polyclonal Antibody; ATP7A (ATPase; Copper Transporting; alpha Polypeptide); Anti -ATP7A (ATPase; anti-ATP7A antibody

• Host: Chicken
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgY
• Specificity: Recognizes human ATP7A. Species Crosreactivity: Mouse and rat.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.

• Applicable Applications for anti-ATP7A antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.; Dilution: Western Blot: 1:1000-1:2000
• Immunogen: Synthetic peptide corresponding to aa1407-1500
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Western Blot (WB)

(Western Blot Test: E coli-derived fusion protein as test antigen. Affi-anti-ATP7A IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.)

Related Product Information for anti-ATP7A antibody

Copper-transporting ATPase 1 is an integral membrane protein cycling constitutively between the trans-golgi network and the plasma membrane. It may supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.

Product Categories/Family for anti-ATP7A antibody

Antibodies; Abs to Enzymes; ATPase

NCBI and Uniprot Product Information

• NCBI GI #: 34222043
• NCBI GeneID: 538
• UniProt Accession #: Q762B6; Q04656; Q59HD1
• Molecular Weight: 30,124 Da
• NCBI Official Full Name: ATP7A
• NCBI Official Synonym Full Names: ATPase, Cu++ transporting, alpha polypeptide
• NCBI Official Symbol: ATP7A
• NCBI Official Synonym Symbols: MK; MNK; DSMAX; SMAX3; FLJ17790
• NCBI Protein Information: copper-transporting ATPase 1; copper pump 1; OTTHUMP00000023593; Cu++-transporting P-type ATPase; Menkes disease-associated protein
• UniProt Protein Name: ATP7A protein
• UniProt Gene Name: ATP7A
• UniProt Entry Name: Q762B6_HUMAN

NCBI Description

This gene encodes a transmembrane protein that functions in copper transport across membranes. The protein localizes to the trans-Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. The protein relocalizes to the plasma membrane under conditions of elevated extracellular copper and functions in the efflux of copper from cells. Mutations in this gene result in Menkes disease, X-linked cutis laxa, and occipital horn syndrome. [provided by RefSeq]