Rabbit ATP6V1D Polyclonal Antibody | anti-ATP6V1D antibody

ATP6V1D Polyclonal Antibody

Cat. Num. AAA2554763

• Gene Names: ATP6V1D; VATD; VMA8; ATP6M
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Affinity Purification
• Synonyms: ATP6V1D; Polyclonal Antibody; ATP6V1D Polyclonal Antibody; ATP6M; V-ATPase 28 kDa accessory protein; V-ATPase subunit D; V-type proton ATPase subunit D; Vacuolar ATP synthase subunit D; Vacuolar proton pump subunit D; VATD; VMA8; anti-ATP6V1D antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 247

• Applicable Applications for anti-ATP6V1D antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Recombinant protein of human ATP6V1D
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using ATP6V1D antibody.)

Related Product Information for anti-ATP6V1D antibody

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein.

Product Categories/Family for anti-ATP6V1D antibody

Cancer; Metabolism; Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 7706757
• NCBI GeneID: 51382
• NCBI Accession #: NP_057078.1
• NCBI GenBank Nucleotide #: NM_015994.4
• UniProt Accession #: Q9Y5K8; Q9Y688; B2RE33
• Molecular Weight: Calculated: 28kDa; Observed: 35kDa
• NCBI Official Full Name: V-type proton ATPase subunit D
• NCBI Official Synonym Full Names: ATPase H+ transporting V1 subunit D
• NCBI Official Symbol: ATP6V1D
• NCBI Official Synonym Symbols: VATD; VMA8; ATP6M
• NCBI Protein Information: V-type proton ATPase subunit D
• UniProt Protein Name: V-type proton ATPase subunit D
• UniProt Gene Name: ATP6V1D
• UniProt Synonym Gene Names: ATP6M; VATD; V-ATPase subunit D

NCBI Description

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq, Jul 2008]

Uniprot Description

Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium.