Rabbit anti-Human ATP5C1 Polyclonal Antibody | anti-ATP5C1 antibody

ATP5C1 Antibody, Biotin conjugated

Cat. Num. AAA7103334

• Gene Names: ATP5F1C; ATP5C; ATP5C1; ATP5CL1
• Reactivity: Human
• Applications: ELISA
• Purity: >95%, Protein G purified
• Synonyms: ATP5C1; Polyclonal Antibody; ATP5C1 Antibody; Biotin conjugated; ATP synthase subunit gamma; mitochondrial; F-ATPase gamma subunit; ATP5C; ATP5CL1; anti-ATP5C1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 298

• Applicable Applications for anti-ATP5C1 antibody: ELISA (EIA)
• Immunogen: Recombinant Human ATP synthase subunit gamma, mitochondrial protein (156-266AA)
• Conjugation: Biotin
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Related Product Information for anti-ATP5C1 antibody

Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

Product Categories/Family for anti-ATP5C1 antibody

Tags & Cell Markers; Metabolism; Signal transduction

NCBI and Uniprot Product Information

• NCBI GI #: 50345988
• NCBI GeneID: 509
• NCBI Accession #: NP_001001973.1
• NCBI GenBank Nucleotide #: NM_001001973.2
• UniProt Accession #: P36542; Q5VYP3; Q6I9V2; Q96AS8; A8KA31
• Molecular Weight: 32,881 Da
• NCBI Official Full Name: ATP synthase subunit gamma, mitochondrial isoform L (liver)
• NCBI Official Synonym Full Names: ATP synthase F1 subunit gamma
• NCBI Official Symbol: ATP5F1C
• NCBI Official Synonym Symbols: ATP5C; ATP5C1; ATP5CL1
• NCBI Protein Information: ATP synthase subunit gamma, mitochondrial
• UniProt Protein Name: ATP synthase subunit gamma, mitochondrial
• UniProt Gene Name: ATP5C1
• UniProt Synonym Gene Names: ATP5C; ATP5CL1

NCBI Description

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14. [provided by RefSeq, Jul 2008]

Uniprot Description

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F1 domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha3beta3. Rotation of the central stalk against the surrounding alpha3beta3 subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.