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Immunohistochemistry (IHC) (Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit anti-Mouse, Human ATF7IP2 Polyclonal Antibody | anti-ATF7IP2 antibody

Anti-ATF7IP2 Antibody (aa318-347) IHC-plus

Gene Names
ATF7IP2; MCAF2
Reactivity
Mouse, Human
Applications
Immunohistochemistry, Western Blot, Flow Cytometry, Functional Assay
Purity
Immunoaffinity purified
Synonyms
ATF7IP2; Polyclonal Antibody; Anti-ATF7IP2 Antibody (aa318-347) IHC-plus; Rabbit Polyclonal to Human ATF7IP2; Human ATF7IP2; MCAF2; ATF7-interacting protein 2; anti-ATF7IP2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Human
Clonality
Polyclonal
Specificity
Human ATF7IP2
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.09% sodium azide
Sequence Length
682
Applicable Applications for anti-ATF7IP2 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes
Flow Cytometry (1:10 - 1:50)
IHC-P (1:100)
WB (1:1000)
Immunogen
ATF7IP2 antibody was raised against kLH-conjugated synthetic peptide from internal region of human MCAF2.
Immunogen Description
KLH-conjugated synthetic peptide from internal region of human MCAF2.
Immunogen Type
Synthetic peptide
Antigen Modification
aa318-347
Target Species
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months.
For long term storage store at -20 degree C.

Immunohistochemistry (IHC)

(Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(MCAF2 Antibody western blot of CEM cell line lysates (35 ug/lane). The MCAF2 antibody detected the MCAF2 protein (arrow).)

Western Blot (WB) (MCAF2 Antibody western blot of CEM cell line lysates (35 ug/lane). The MCAF2 antibody detected the MCAF2 protein (arrow).)

Western Blot (WB)

(MCAF2 Antibody western blot of mouse stomach tissue lysates (35 ug/lane). The MCAF2 antibody detected the MCAF2 protein (arrow).)

Western Blot (WB) (MCAF2 Antibody western blot of mouse stomach tissue lysates (35 ug/lane). The MCAF2 antibody detected the MCAF2 protein (arrow).)

Flow Cytometry (FC/FACS)

(MCAF2 Antibody flow cytometry of CEM cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (MCAF2 Antibody flow cytometry of CEM cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-ATF7IP2 antibody
ATF7IP2 Antibody, MCAF2 Antibody, ATF7-interacting protein 2 Antibody Description: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity Probable.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
60,894 Da
NCBI Official Full Name
activating transcription factor 7-interacting protein 2 isoform 1
NCBI Official Synonym Full Names
activating transcription factor 7 interacting protein 2
NCBI Official Symbol
ATF7IP2
NCBI Official Synonym Symbols
MCAF2
NCBI Protein Information
activating transcription factor 7-interacting protein 2
UniProt Protein Name
Activating transcription factor 7-interacting protein 2
UniProt Gene Name
ATF7IP2
UniProt Synonym Gene Names
MCAF2; ATF7-interacting protein 2
UniProt Entry Name
MCAF2_HUMAN

Uniprot Description

ATF7IP2: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable). Belongs to the MCAF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 16p13.13

Cellular Component: cytoplasm; nucleolus; nucleus

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent

Research Articles on ATF7IP2

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Product Notes

The ATF7IP2 atf7ip2 (Catalog #AAA2400312) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ATF7IP2 Antibody (aa318-347) IHC-plus reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's ATF7IP2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB), Flow Cytometry (FC/FACS). Flow Cytometry (1:10 - 1:50) IHC-P (1:100) WB (1:1000). Researchers should empirically determine the suitability of the ATF7IP2 atf7ip2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATF7IP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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