NCBI and Uniprot Product Information
NCBI Description
This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Uniprot Description
ATE1: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues. Belongs to the R-transferase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.3.2.8; Transferase
Chromosomal Location of Human Ortholog: 10q26.13
Cellular Component: cytoplasm; nucleus
Molecular Function: arginyltransferase activity; protein binding
Biological Process: protein arginylation
Research Articles on ATE1
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Product Notes
The ATE1 ate1 (Catalog #AAA9417259) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATE1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ATE1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:200-1000. Researchers should empirically determine the suitability of the ATE1 ate1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATE1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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